Clinical

Coverage from the 64th Scientific Sessions of the American College of Cardiology.

A study published in Nature Medicine highlights how genetic data can be translated in disease prevention and evidence-based clinical management.

Evidence-Based Diabetes Management invited the YMCA's Jonathan Lever, vice president for health strategy and innovation, to comment on his organization's involvement with the National Diabetes Prevention Program.

Researchers at Cancer Research UK have challenged the current standard of care in advanced ovarian cancer patients. Results of their study, published in Lancet, found that administering chemotherapy prior to surgery can have huge benefits on health outcomes and the patient's quality of life.

A secondary analysis on results of the CAPTION trial pointed to a role for pharmacists in helping tailor the treatment regimen for patients with hypertension, although it did not improve blood pressure control.

Until this study, no one had reported on how the discrepancies between adult and pediatric guidelines might affect treatment for young adults.

A Science study found that recurrent mutations in the promoter of the telomerase gene, TERT, could be responsible for overexpression of telomerase in a majority of cancers, thereby sustaining the replicative potential of cancer cells.

Two new insulins marketed by Sanofi offer improved options for patients: Toujeo is longer acting than its predecessor, Lantus. Afrezza, an inhaled insulin, is gaining praise from patients, if not from Wall Street.

Coverage from the 64th Scientific Sessions of the American College of Cardiology.

Risk factors associated with diabetic ketoacidosis typically do not change. Preventing DKA should focus on identification of those most at risk and educating them good self-care to avoid incidents.

Coverage from the 64th Scientific Sessions of the American College of Cardiology.

The editor in chief of Evidence-Based Diabetes Management welcomes those coming to the ADA Scientific Sessions to attend sessions featuring faculty from Joslin Diabetes Center.

Coverage from the 64th Scientific Sessions of the American College of Cardiology.

Coverage from the 64th Scientific Sessions of the American College of Cardiology.

Findings of a study published in Infection Control & Hospital Epidemiology show that 95% of inpatients at a VA hospital in Minneapolis with an incorrect or indeterminate diagnosis, were given inappropriate antibiotics, as opposed to 38% who were accurately diagnosed, yet administered incorrect medication.

Data presented at the American Urological Association in New Orleans show a 50% drop in PSA testing in the years since the USPSTF issued its controversial D recommendation. Some see a "chilling" effect, but not all see a problem.

Large data sets like SEER need better quality control checks and researchers and clinicians who use these data sets should also consider using secondary data analyses that answer specific research questions. This is the advice of a senior urologist following the removal of the PSA data.

The findings in Diabetes Care served as early confirmation of what some had feared: a bifurcated Medicaid system will lead to an American of haves and have-nots in healthcare.

An evidence review supports a proposed USPSTF recommendation to update how the healthcare system screens for prediabetes.

Major professional and advocacy groups back legislation to create access to the National Diabetes Prevention Program.

With the right support, community providers can offer an effective approach to promoting population health and preventing chronic disease.

The study, conducted by researchers at the Henry Ford Hospital, found that complications associated with robot-assisted radical prostatectomies were higher in low-volume hospitals, with relatively inexperienced staff.

The CDC's director of the Division of Diabetes Translation discusses the scientific evidence that supports the need for both lifestyle interventions and population-level efforts to combat type 2 diabetes in the United States.

Studies offer insights for patients with atrial fibrillation and type 2 diabetes mellitus, with more results to come.

Karen Davis, director of Roger C. Lipitz Center for Integrated Health Care at Johns Hopkins University, says increasing resources available for home treatments and services and support for family caregivers of the elderly and those with debilitating diseases might work to reduce reliance on costly nursing homes for those afflicted.

The FDA said it had received 20 reports in the 15 months since the first of the SGLT2 inhibitor class was approved, and had continued to receive reports since that time. All drugs in the class were included in the safety communication.

The study, published in Cancer, found a 14% higher rate of obesity among childhood cancer survivors in their surveyed population, compared to the federal numbers.

Venous thromboembolism during or after recent hospitalization for medical illness contributes a substantial economic burden to society across all hospital and ambulatory care delivered.

In his own words, "The practice of evidence-based medicine means integrating individual clinical expertise with the best available external clinical evidence from systematic research."