Macitentan Safety, Effectiveness in PAH Confirmed in New Analysis
November 3rd 2022Two data sets from patients with severe pulmonary arterial hypertension (PAH) show the benefits of macitentan (Opsumit) monotherapy despite guidelines calling for combination therapy, even among patients with World Health Organizational functional class I-II disease.
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As Medical Falsehoods Persist, Concerns About Future Pandemic Readiness Grow
November 3rd 2022Physicians and scientists are worried about the future pandemic preparedness, and the reasons why are largely due to social and political influences, according to a keynote speech and panel discussion on the first day of Kidney Week 2022.
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Change in Smoking Status and Subsequent BMI Change Linked to NAFLD Risk
November 3rd 2022Across 4 types of smoking status groups, nonalcoholic fatty liver disease (NAFLD) risk significantly increased among participants who saw an increase in body mass index (BMI) and decreased among participants whose BMI went down.
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Glomerular Filtration Rate Based on Cystatin C More Accurate for Predicting CVD, Mortality
November 3rd 2022A prospective population-based cohort study found that glomerular filtration rate based on cystatin C was more sensitive and specific for cardiovascular disease (CVD) and mortality risks compared with glomerular filtration rate based on creatinine.
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The HHS renewed the national public health emergency for the monkeypox outbreak in the United States; more demand for amoxicillin has led to a nationwide shortage as respiratory illnesses continue to spread; a drug already approved for weight loss in adults has demonstrated promise in teenagers aged 12 to 17 years.
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FDA advisers met to discuss alternatives to the infrared light used in pulse oximeters, which can be absorbed by melanin; FDA warns of a national shortage of tracheostomy tubes, especially for pediatric patients; 1 in 5 deaths among adults aged between 20 and 49 years is due to excessive drinking.
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Intermediate Parkinson Disease Associated With Significant Clinical, Economic Burden
November 2nd 2022A poster presented at Academy of Managed Care Pharmacy Nexus 2022 shows that patients with intermediate Parkinson disease place a significant resource burden on the US health care system in regard to treatment, emergency department visits, and admissions to rehabilitation centers.
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Dr Neil Gross Discusses the Implications of pCR on Additional Treatment in Skin Cancer
November 2nd 2022Neil D. Gross, MD, FACS, head and neck surgeon and director of clinical research in the Department of Head and Neck Surgery at The University of Texas MD Anderson Cancer Center, discusses the results of study he and his team conducted in the setting of resectable stage II to IV cutaneous squamous cell carcinoma.
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Hidradenitis Suppurativa ED Readmission Linked to Opioid Prescribing, Medicaid Insurance
November 1st 2022Emergency department (ED) readmission was more common than dermatology follow-up among patients with hidradenitis suppurativa (HS) within 30 and 180 days of initially presenting to the ED, with patients with Medicaid coverage and those who had an opioid prescribed were more likely to return.
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Dr Amresh Raina Illuminates Top Concerns in Asymptomatic Heart Failure
November 1st 2022Risk factors not properly addressed in patients with asymptomatic heart failure, such as high blood pressure and having diabetes or mild heart valve problems, can lead to structural heart problems or heart failure itself, noted Amresh Raina, MD, of the Allegheny Health Network in Pittsburgh, Pennsylvania.
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FDA Rejects Bulevirtide for Hepatitis D, Compensated Liver Disease
November 1st 2022The FDA has issued a complete response letter to Gilead Sciences, indicating that it cannot approve the company’s first-in-class investigational entry-inhibitor, bulevirtide, for the treatment of chronic hepatitis D virus infection and compensated liver disease.
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Pfizer’s maternal respiratory syncytial virus (RSV) vaccine was found to be highly effective in infants' first 6 months of life; survey shows long COVID-19 is more common among women than men; some voters worry that a Republican-controlled Congress could put science and science policy on the line.
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Diabetic Kidney Disease Progression Associated With Changes in Muscle, Fat Amounts
November 1st 2022Patients with type 2 diabetes with a high to very high prognostic risk of diabetic kidney disease were more likely to have a reduced rectus femoris cross-sectional area, a measure of muscle mass in the lower body, and an increased visceral fat area.
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Non–Driver Gene Mutations May Hold Predictive Value in ET and PV
November 1st 2022A recent study supports the notion that non–driver mutations in essential thrombocythemia (ET) and polycythemia vera (PV) have predictive value and found that a proposed international prognostication model may be useful for Japanese patients.
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Susan E. Quaggin, MD, FASN, president of the American Society of Nephrology (ASN) for the 2021-2022 term, discussed the major focuses and breakthroughs in nephrology to be presented at Kidney Week 2022, which include novel treatments for common and rare kidney diseases, as well as efforts to address disparities for transplant and care access.
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Identifying SE in Initial Asthma Screening May Help Promote Precision Medicine
October 31st 2022The retrospective findings showed that searching for Staphylococcus aureus and its enterotoxins (SE) when initially screening patients for asthma can help with identifying a targeted treatment option by improving phenotyping and predicting comorbidities.
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