What We’re Reading: Medicare Coverage of Aduhelm; US Life Expectancy Drops; Pandemic-Induced Trauma
April 8th 2022CMS issues final plan for aducanumab (Aduhelm) coverage; 2021 sees further drop in US life expectancy; individuals have presented with symptoms of trauma throughout the COVID-19 pandemic.
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Older EoE Patients More Likely to Respond to Topical Corticosteroids, Study Finds
April 8th 2022Recent clinical trials have excluded older patients with eosinophilic esophagitis (EoE) from participating; however, patients aged 65 years and older are more likely to respond to topical corticosteroids than their younger counterparts.
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Genomic Profiling Utility for Targeted Therapy Selection Shown in Advanced GI Cancers
April 8th 2022The clinical utility of genomic profiling was demonstrated in patients with advanced gastrointestinal (GI) cancers whose access to targeted therapies based on tissue-based assay findings was similar to those with non-GI cancers.
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Equivalent Safety, Efficacy Between Herceptin and Trastuzumab Biosimilar for Gastric Cancer
April 7th 2022A trastuzumab biosimilar was found to have similar safety and efficacy with the reference product (Herceptin) in patients with advanced gastric cancer, a population previously excluded from bioequivalence studies for trastuzumab biosimilars.
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Dr Chelsee Jensen on the Solution to Stocking Multiple Biosimilars for the Same Reference Product
April 7th 2022Chelsee Jensen, PharmD, pharmaceutical formulary manager at the Mayo Clinic, provides her take on why practices will have to continue to stock multiple biosimilars for the same reference product.
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Incremental Steps Helpful but Not Enough to End Underinsurance Issue, Panelists Say
April 7th 2022Without addressing rising costs, the problem of underinsurance in health care coverage will remain, said panelists at the 2022 V-BID Summit, discussing some of the smaller steps that are being proposed or are already in place to try to ease the financial burden.
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Higher DKA Rates Seen in Black Patients With T1D Throughout COVID-19
April 7th 2022Compared with other racial/ethnic groups, Black patients with type 1 diabetes (T1D) presented to medical centers with diabetic ketoacidosis (DKA) more often throughout the COVID-19 pandemic, regardless of COVID-19 infection.
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Dr Stephen Rozzo on Regulatory Nature of Tildrakizumab for Psoriasis
April 7th 2022Stephen Rozzo, PhD, associate vice president and head, Biologics Medical Affairs, Sun Pharma, North America, explains tildrakizumab’s mechanisms of action in the treatment of psoriasis and how the drug differs from other approved biologics.
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Increasing Health Equity to Reduce Disparities in Value-Based Care
April 7th 2022At the 2022 V-BID Summit, hosted by the Center for Value-Based Insurance Design at the University of Michigan, representatives of CMS and the Commonwealth Fund gave an update on the efforts to monitor, evaluate, and improve health equity in the United States.
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What We’re Reading: Variant-Specific Boosters; CDC Revamp; EPA Asbestos Ban
April 7th 2022A panel of experts advised the FDA to support the development of COVID-19 variant-specific booster doses; the CDC is undergoing a month-long review in efforts to revamp the agency; the Environmental Protections Agency (EPA) proposed a rule to ban asbestos.
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Understanding the Tumor Microenvironment of Cholangiocarcinoma
April 7th 2022The authors found that the relationship between immunosuppressive cells and effector T cells in hilar and distal cholangiocarcinoma has important implications for treatment, in that the tumor microenvironment would likely need to be primed for a treatment strategy to be effective.
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Protease Inhibitor–Based ART Associated With Babies Born Small or Very Small
April 6th 2022A large systematic review on pregnant women living with HIV found that protease inhibitor–based antiretroviral therapy (ART) use was associated with increased risk of babies being born small or very small for their gestational age, but not with other adverse pregnancy outcomes.
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Consider Screening Patients With Food Allergy for EoE, Pilot Study Says
April 6th 2022A recent study found a correlation in patients with an IgE-mediated food allergy (IgE-FA) reporting symptoms of eosinophilic esophagitis (EoE), leading researchers to conclude screening for EoE may be beneficial.
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Dr Dennis Scanlon on Barriers for Learning Health Care Systems
April 6th 2022Dennis P. Scanlon, PhD, professor of health policy and administration at Pennsylvania State University and editor-in-chief of The American Journal of Accountable Care®, talks about major systemic and fundamental barriers to health systems becoming learning health systems.
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Real-world Data Show Benefits of Increased Lung Cancer Screening but Persistent Disparities
April 6th 2022Although the widespread use of low dose computed tomography screening for lung cancer has led to improved mortality in recent years, disparities in uptake persist throughout the United States.
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What We’re Reading: Long COVID-19 Research; Oklahoma Abortion Ban; Walgreens Opioid Lawsuit
April 6th 2022President Joe Biden announced plans to increase research on long COVID-19; the Oklahoma House voted 70-14 in favor of a near-total abortion ban; Walgreens is going to trial in Florida’s opioid epidemic lawsuit.
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Dr Marc-Andre Cornier Discusses COVID-19's Impact on a Weight Loss Intervention Program
April 6th 2022Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, explains recent research on a behavioral weight loss intervention.
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Baricitinib Linked With Improved Skin Pain Severity, Positive QOL in Atopic Dermatitis
April 5th 2022Patients with atopic dermatitis who achieved rapid changes in skin pain severity with the Janus kinase inhibitor baricitinib were associated with clinically significant improvement in Dermatology Life Quality Index scores.
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