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Adult patients with moderate-to-severe atopic dermatitis (AD) in the phase 3 BREEZE-AD7 study showed sustained improvement of AD signs and symptoms after 68 weeks with combination treatment of bariticitinib and topical corticosteroids.

A pair of abstracts presented during this year’s 64th American Society of Hematology Annual Meeting and Exposition explored barriers to treatment for sickle cell disease (SCD).

2022's most-read news about the pandemic included the impact of COVID-19 on patients with asthma, the Biden administration's plans to advance vaccination and other initiatives, information about when SARS-CoV-2 is at its most infectious, and more.

For this analysis, the Japan Pulmonary Hypertension Registry provided data from 2008 to 2021 on patients with diagnosed portopulmonary hypertension (PoPH).

Cemiplimab with chemotherapy appears to offer value comparable to other options and may be "an important tool to use" in first-line treatment of non-small cell lung cancer (NSCLC), said Davey Daniel, MD, chief medical officer for OneOncology, lung cancer specialist.

The top 5 most-read articles about diabetes featured stories on FDA approvals, drug prices, and the effectiveness of vitamin D in diabetes prevention, among others.

In this study, researchers treated 37 basal cell carcinoma (BCC) lesions from 30 patients, with follow-ups at 5 time points after baseline examination.

The new federal spending bill includes changes to Medicaid enrollment, postpartum coverage, and other health programs; new research shows widened disparities among US adults with diabetes using insulin; in 2022, the Drug Enforcement Administration confiscated more than 379 million fentanyl doses.

The most-viewed eosinophilic esophagitis (EoE) content of the year covered new developments in treatment options for EoE, the prevalence of EoE in the allergic disease population, and the impact of EoE on a child’s well-being.

Jessica Allegretti, MD, MPH, medical director of the Crohn's and Colitis Center, Brigham and Women's Hospital, explained the mechanism of action for Rebyota, the first fecal transplant therapy approved by the FDA for the prevention of recurrent Clostridioides difficile infection (CDI) in individuals 18 years and older, following antibiotic treatment for recurrent CDI.

In heart failure this year, value-based care, left ventricular ejection fraction, and disease prevention were among the most popular topics discussed.

A research letter examined the clinical presentation, disease severity, associated comorbidities, and management of hidradenitis suppurativa in older adults aged 65 years or older.

A new study found that short sleep duration and high siesta ratio were associated with a higher risk of hypertension and elevated risk of cardiovascular diseases.

Incidence of Parkinson disease in North America was 50% higher than previous estimates of 60,000 diagnoses annually.

The top 5 most-read content in leukemia and lymphoma for 2022 addressed chimeric antigen receptor T-cell therapy, updates in recommended treatment, and President Joe Biden’s announcement on the return of the Cancer Moonshot.

Diagnoses of psoriatic arthritis, rheumatoid arthritis, axial spondyloarthritis, or undifferentiated inflammatory arthritis saw a dramatic decline during the early stages of the COVID-19 pandemic.

A new study has found that prolonged screen time may cause increased symptoms of dry eye disease (DED) in children.

A pair of abstracts presented at this year’s 64th American Society of Hematology Annual Meeting and Exposition bear out the significant transfusion-free rate at 3 years following beti-cell administration and marked improvements in patient-reported outcomes, including the ability to work and be physically active.

Content published on AJMC.com focusing on automated insulin delivery devices over the past year highlighted utilization of these devices by age, compared different types of systems, looked at barriers to uptake, and examined equity issues standing in the way of access.

A new study has found that Mexican Americans and non-Hispanic Black Americans had low rates of glycemic control compared with non-Hispanic White Americans.

Among young adults, 2-year cancer survival increased more in states with expanded Medicaid coverage; some pharmacies implemented purchase limits to help combat children’s medicine supply shortages; an FDA advisory panel will meet next month to discuss the state of the COVID-19 pandemic.

The top biosimilars content of 2022 reviewed perceptions around switching to a trastuzumab biosimilar, drug costs, and the successful implementation of biosimilars in practice.

New study findings call into question the necessity of spirometry as a criterion for participation in palliative care research among patients with chronic obstructive pulmonary disease (COPD).

A retrospective study found roxadustat to be more effective in improving hemoglobin levels in patients who had with chronic kidney disease (CKD) compared with recombinant human erythropoietin.

Overall survival for patients with combined hepatocellular-cholangiocarcinoma is poor, but those who received adjuvant transarterial chemoembolization (TACE) after surgery had a prolonged recurrence-free survival (RFS).

This new study, which followed patients up to 6 months after functional endoscopic sinus surgery, evaluated results using objective and subjective measures.

Martin Levine, MD, MBA, chief medical officer at the PolyClinic at Optum Washington, describes why caregivers need more resources to adequately manage patients with Alzheimer disease and what clinics can do to ensure access to those resources.

Eli Lilly is experiencing a shortage of the diabetes drug tirzepatide (Mounjaro); a data breach has caused over 200,000 Medicare enrollees to receive new identification cards; a restructuring of the current model for developing and selling antibiotics could be a solution to shortages and drug-resistant germs.