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Fewer patients opt to skip therapy for their multiple myeloma (MM) despite progressive disease than previously thought, a new study suggests.

Initiation of sodium-glucose cotransporter-2 inhibitors (SGLT2is) was associated with a 34% lower rate of recurrent gout flare compared with initiation of dipeptidyl peptidase 4 inhibitors (DPP-4is).

Select lifestyle practices can help to reduce particulate matter (PM) concentrations and exposure in patients with chronic obstructive pulmonary disease (COPD), which can affect clinical outcomes.

A study conducted in Japan found that short-term exposure to statins was not associated with an increased risk of open-angle glaucoma (OAG) in a population with dyslipidemia.

Investigators will submit data from the phase 3 ENHANCE trial evaluating magrolimab plus azacitidine in higher-risk myelodysplastic syndromes for presentation at a future medical meeting.

Democratic House forerunners present legislation to expand drug cost lowering procedures; President Joe Biden presents an advanced cancer research push; a Senate panel advances a pharmacy benefit manager (PBM) reform bill.

Lymphoplasmapheresis (LPE) was also completed with fewer replacements compared with plasma exchange (PE) for myasthenia gravis (MG).

On this episode of Managed Care Cast, we speak with the lead researcher from a study published in the July 2023 issue of The American Journal of Managed Care® on whether social determinants of health is a predictor for identifying high-cost utilizers among those with commercial health insurance.

Highly resourced accountable care organizations (ACOs) were more likely to offer digital health services.

Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin subtype in individuals living with HIV.

Better diagnostic tests and wider availability of low-cost vaccines would help further decrease cases, the authors said

Prediction models are needed to identify individuals at high risk for lung cancer who are former smokers and for whom low-dose computed tomography screening is not recommended, according to one study.

Investigators recommend including domestic violence and abuse as risk factors in public health strategies that target atopic disease assessments.

Among people living with HIV receiving antiretroviral therapy, those taking 4-mg pitavastatin daily were 35% less likely than those taking placebo to experience a major cardiovascular event over 5 years of follow-up.

Following prostatectomy in patients with recurrent prostate cancer, researchers analyzed post–salvage radiotherapy prostate-specific antigen (PSA) values and the percentages of PSA decline to anticipate patient survival rates.

A class-action lawsuit was filed against Cigna for allegedly wrongfully rejecting thousands of claims using an algorithm; Black women still have a fetal mortality rate double the national average despite declining from that of recent years; the CDC is investigating the source of ground beef causing a multistate salmonella outbreak.

While antibiotic treatment is highly effective, soft rick relapsing fever (STRF) can result in severe health complications, including death, if not treated in a timely manner.

The shrinking gap was mainly driven by mobile device use.

The playbook from the 3 organizations highlights 5 best practices for data sharing from organizations with real-world experience in value-based care arrangements.

Women with HIV who reported heavy alcohol use were more likely to have lower self-reported health status, but this association was not seen in men with HIV.

People with psoriasis were also more likely to have pulmonary comorbidities compared with those who did not have psoriasis.

The individual first received their multiple myeloma (MM) diagnosis in 2019.

School-based asthma education was found to be effective in increasing asthma knowledge both in those who have never received asthma education and those with prior knowledge, a study finds.

A study conducted in Colombia found that detection of respiratory syncytial virus (RSV) was associated with air pollutants, the health care system, and weather.

The COVID-19 pandemic had a particularly negative impact on the uptake of non–COVID-19 vaccines for adults in some countries. Even countries with great progress in adult vaccination prior to the pandemic saw a decline after the pandemic.

Political leanings appear to be associated with mortality during the COVID-19 pandemic; the Biden administration takes steps to ensure parity between mental and physical health benefits; extreme heat and air pollution amplify heart attack risk.

Dayna Johnson, PhD, MPH, MSW, MS talks about the necessity of community partnerships as the recipient of this year’s Associated Professional Sleep Societies (APSS) Diversity, Equity, and Inclusion Leadership Award at SLEEP 2023 and how inquiring into the community is vital for integrating healthy sleep practices.

New research suggests that when cancer cells are under stress, cellular chaperone protein GRP78 alters its behavior and migrates to the cell's nucleus, where it modifies gene activities and allows cancer cells to become more mobile and invasive.

Stress can harm different areas of sleep health in young adults who are good sleepers.

The researchers noted that their paper is the first, to their knowledge, to report on a case of thrombocytopenic purpura (TTP) in a patient with metastatic renal cell carcinoma (RCC).