What We’re Reading: Childhood Obesity Counseling; Humana Lawsuit; AI Use Concern
December 13th 2023The US Preventive Services Task Force (USPSTF) recommended that children with obesity receive intensive counseling at age 6 to promote healthy diet and exercise habits; a new survey found that the majority of American patients are wary of their doctors using artificial intelligence (AI); a class-action lawsuit was filed Tuesday against health insurer Humana for using an AI algorithm that systemically denies seniors rehabilitation care recommended by their doctors.
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Faricimab Increases Fluid-Free Interval, Extends Dosing Interval in Patients With AMD
December 12th 2023Patients with age-related macular degeneration (AMD) who were not responsive to anti–vascular endothelial growth factor agents were able to increase their fluid-free intervals with faricimab.
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Pivotal Results Show Revumenib Holds Promise for Patients With KMT2Ar Acute Leukemia
December 12th 2023In AUGMENT-101, patients with R/R KMT2Ar acute leukemia had high overall response rates; despite being heavily pretreated, 40% were able to proceed to transplant and the KMT2Ar cohort was stopped early.
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Frontline Daratumumab Plus VRd Outperforms Standard VRd Alone in Multiple Myeloma
December 12th 2023A late-breaking abstract presented at the American Society of Hematology Annual Meeting and Exposition supports the addition of subcutaneous daratumumab to standard-of-care bortezomib, lenalidomide, and dexamethasone (VRd) in patients with newly diagnosed multiple myeloma who are eligible for autologous stem cell transplantation.
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Metformin Does Not Improve Neonatal Outcomes for Pregnant Patients With Diabetes
December 12th 2023Adding metformin to the insulin regimen for pregnant patients with preexisting type 2 diabetes (T2D) or gestational diabetes diagnosed early in pregnancy did not reduce the risk of neonatal adverse outcomes.
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Zanubrutinib May Be Viable Option After Acalabrutinib Intolerance in B-Cell Malignancies
December 11th 2023Patients with B-cell malignancies who were intolerant to treatment with acalabrutinib experienced clinically meaningful benefits when treated with zanubrutinib, suggesting zanubrutinib may be a viable treatment option for this population.
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Eye Changes After Cataract Surgery Associated With Diabetic Retinopathy
December 11th 2023Patients receiving uncomplicated phacoemulsification surgery for cataracts had greater increases in macular and choroidal thickness if they had early diabetic retinopathy without preoperative diabetic macular edema.
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Short Sleep Duration Linked With All-Cause Mortality in Patients With Sleep Apnea
December 11th 2023New results from the Sleep Heart Health Study (SHHS) identified a significant association between sleep duration and all-cause mortality among individuals grappling with obstructive sleep apnea (OSA).
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Second-Line Axi-Cel Prolongs Survival Over Standard of Care in Elderly Patients With R/R LBCL
December 11th 2023The administration of axicabtagene ciloleucel in the second-line setting improved overall survival and progression-free survival vs standard-of-care treatment in patients with relapsed/refractory large B-cell lymphoma who are at least 65 years of age.
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ICYMI: Highlights From the ACCC Fall National Oncology Conference
December 11th 2023This year’s top content from the fall meeting of the Association of Community Cancer Centers (ACCC) highlights both treatment gains made through innovative referral, screening, and assistance initiatives and the ongoing need to improve health equity and research inclusivity.
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Is Genome Editing the Next Step in Immunotherapy Innovation? Experts Think So
December 11th 2023Presenters at the American Society of Hematology Annual Meeting and Exposition agreed that novel strategies, such as CRISPR and base editing, have potential to fine-tune the latest immunotherapy advancements to increase the efficacy and durability of a range of treatments.
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