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Patients with metastatic colorectal cancer (CRC) who experience colon perforation may have similar survival times to those without perforation.

The commercial market got slightly less competitive while the Medicare Advantage market got a little more competitive, but both markets remain highly concentrated.

BCMA-directed CAR T-cell therapy anitocabtagene autoleucel demonstrated a 76% complete remission rate and 89% negative minimal residual disease in patients with relapsed/refractory multiple myeloma.

Patients with age-related macular degeneration (AMD) who were not responsive to anti–vascular endothelial growth factor agents were able to increase their fluid-free intervals with faricimab.

In AUGMENT-101, patients with R/R KMT2Ar acute leukemia had high overall response rates; despite being heavily pretreated, 40% were able to proceed to transplant and the KMT2Ar cohort was stopped early.

Ciprofloxacin, ceftriaxone, and piperacillin/tazobactam showed the greatest associations with adverse drug reaction case reports related to C difficile.

A late-breaking abstract presented at the American Society of Hematology Annual Meeting and Exposition supports the addition of subcutaneous daratumumab to standard-of-care bortezomib, lenalidomide, and dexamethasone (VRd) in patients with newly diagnosed multiple myeloma who are eligible for autologous stem cell transplantation.

Investigators explored the genetic relationship between psoriatic disease and serum lipid levels.

Adding metformin to the insulin regimen for pregnant patients with preexisting type 2 diabetes (T2D) or gestational diabetes diagnosed early in pregnancy did not reduce the risk of neonatal adverse outcomes.

End-of-year victory for lawmakers as health care policies pass in the House; insurance limitations prompt concerns over access to semaglutide (Ozempic) for diabetes; a legal battle ensues over the fate of abortion laws in Arizona.

Predicting clinical outcomes in patients with colorectal cancer (CRC) could be done using the novel comprehensive blood indicator PSI.

Growing misinformation around COVID-19 vaccines may have resulted in changes in parents’ trust in vaccines.

A medication monitoring program using medication bottles waws found to be effective in patients with sickle cell disease (SCD), though the usage will need additional support.

Patients with B-cell malignancies who were intolerant to treatment with acalabrutinib experienced clinically meaningful benefits when treated with zanubrutinib, suggesting zanubrutinib may be a viable treatment option for this population.

A trial comparing baricitinib against placebo in people with new-onset type 1 diabetes suggests use could contribute to the preservation of β-cell function.

Patients receiving uncomplicated phacoemulsification surgery for cataracts had greater increases in macular and choroidal thickness if they had early diabetic retinopathy without preoperative diabetic macular edema.

New results from the Sleep Heart Health Study (SHHS) identified a significant association between sleep duration and all-cause mortality among individuals grappling with obstructive sleep apnea (OSA).

The administration of axicabtagene ciloleucel in the second-line setting improved overall survival and progression-free survival vs standard-of-care treatment in patients with relapsed/refractory large B-cell lymphoma who are at least 65 years of age.

Infants with HIV could be spared from requiring lifetime antiretroviral (ART) if treated within hours of birth to disrupt formation of HIV viral reservoirs.

The Biden administration proposed new efforts that it says will promote competition, transparency, and affordability in the health care industry.

This year’s top content from the fall meeting of the Association of Community Cancer Centers (ACCC) highlights both treatment gains made through innovative referral, screening, and assistance initiatives and the ongoing need to improve health equity and research inclusivity.

CDC revealed nationally representative estimates of chronic fatigue; the proposed merger between Cigna and Humana has been terminated over financial terms and shareholder skepticism; ChatGPT provides inaccurate responses to medication queries.

Presenters at the American Society of Hematology Annual Meeting and Exposition agreed that novel strategies, such as CRISPR and base editing, have potential to fine-tune the latest immunotherapy advancements to increase the efficacy and durability of a range of treatments.

Chronic obstructive pulmonary disease (COPD) is associated with fatal events in the long-term prognosis of stroke, but the association between COPD and short-term death in patients with stroke is insignificant.

Of patients in the atopic dermatitis (AD) cohort, 36.6% developed at least 1 comorbidity amid follow-up compared to 28.5% in the non-AD reference cohort.

These new data highlight key points about the timeline of benefits for those who quit smoking cigarettes, including respiratory and cardiovascular benefits.

Although direct-mail self-sampling significantly increased cervical cancer screening, the opt-in approach only minimally increased screening.

The decision was supported by efficacy data from 36 patients from the ongoing phase 1/2 HGB-206 trial (NCT02140554) and 2 patients in the phase 3 HGB-210 trial (NCT04293185). It was the second approval from FDA for a gene therapy for sickle cell disease.

Recent decades have seen marked improvements in hematological cancer outcomes and an expanded armamentarium of therapies, but novel treatments require updated strategies that are not always easy to fine-tune, according to presenters at the 2023 American Society of Hematology Annual Meeting and Exposition.

A phase 4 study found severe asthma can be controlled using biologic therapies, without the addition of high-dose inhaled steroids.