Parkinson Disease

The Personal KinetiGraph (PKG) Movement Recording System may be effective for routine clinical care of patients with Parkinson disease (PD), according to a recent study.

Greater non-motor symptom burden may be associated with thalamic atrophy in Parkinson disease (PD), suggesting that the thalamus has a significant role in processing sensory information including visceral afferent from the gastrointestinal tract and regulating states of sleep.

Performance on a manual dexterity test can act as an objective behavior marker that can aid in detecting the prodromal stage of patients with Parkinson disease.

Parkinson disease significantly impacts an individual’s quality of life (QoL); however, many spouses and family’s QoL and finances are also affected through increased healthcare and privately borne costs as the condition progresses, according to a recent study.

Researchers have identified a group of genetic variants related to the starting point of Parkinson disease.

A recent study investigated whether gait parameters were implicated in motor symptoms or the risk of falling, fining that backward gait (BG) dynamics were more impaired in patients with Parkinson's disease.

A meta-analysis suggests that patients with bipolar disorder have a much greater risk of developing Parkinson disease (PD).

A higher-than-normal body mass index (BMI) at the time of a diagnosis of Parkinson disease (PD) has a protective effect against cognitive decline and the conversion to dementia, a recent study indicated.

Pimavanserin may be an effective treatment option for patients with Parkinson disease who develop Parkinson disease psychosis, according to a recent study published by Neuropsychiatric Disease and Treatment.

Here are the top 5 articles for the month of September.

Cognitive status may be affected by the relationship of Parkinson disease (PD) and affective theory of mind through the involvement of visuospatial abilities (VSA), a recent study reported.

Researchers studied a particular mutation in a gene linked to Parkinson.

Researchers investigated current evidence linking genetic variation to deep brain stimulation treatment and outcomes in Parkinson disease (PD), finding a promising development where genetic profiling may be important for clinicians to personalize medical and surgical therapy for patients.

Terazosin, a drug used to treat enlarged prostate, may also be able to slow the progression of Parkinson disease.

A study investigating the functional connectivity of the praxis network in patients in the early stages of Parkinson’s disease (PD) found that dopaminergic therapy may normalize praxis abilities and related praxis networks during the early stages of the disease by facilitating the propagation of long-term representations of object-related actions to motor execution areas.

The research found that aerobic exercise for 30 to 45 minutes for 3 times a week had an effect similar to that of several conventional Parkinson drugs in patients with mild severity.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

A recent study investigating orthostatic hypotension (OH)—a common condition among patients with Parkinson disease—found that the causality between OH and dementia may be bidirectional and early diagnosis is important to improve long-term prognosis.

A population-based study examining soda consumption in 10 European countries found that soft drinks were linked to a greater risk of death, as well as the chance of dying from Parkinson disease, although that connection needs additional research.

The relationship between cognitive impairment and symptomatic convergence insufficiency in Parkinsonian disorders has not been previously investigated.

Using a body-worn sensor to detect falls at home is feasible for elderly individuals, including those with Parkinson disease, who have a higher risk of falling, according to new study findings.

A new study has found a dose-dependent relationship between coffee consumption and reduced severity of tremors in men with Parkinson disease.

Researchers recommended strategies for providers to think about when managing this population.

Researchers said taking genetic variability into account in the future will be helpful not only to understand the course of Parkinson disease but also to minimize heterogeneity in clinical trials.

Researchers aiming to better understand the role of estrogen in the development of Parkinson disease (PD) and its potential as a treatment found that brain-selective estrogen therapy resulted in motor improvements in male mice with PD-like symptoms.

The survey aimed to better understand the perceptions, experiences, and educational needs of patients who have nonmotor symptoms of Parkinson disease as well as their caregivers.

An analysis of patients’ and caregivers’ willingness to participate in genetic studies on Parkinson disease found that although overall levels of motivation were similar in Hispanic and non-Hispanic patients, the reasons behind this interest varied between the groups.

Female patients who are homebound with advanced Parkinson disease (PD) are more likely to lack any caregiver and more likely to be single or widowed, according to a report published this week.

Findings of a retrospective study show that comorbid psychosis and depression in patients with Parkinson disease are associated with greater disease severity and higher healthcare utilization.

Results of a study on patients with early-stage Parkinson disease (PD) add to the evidence showing an association between PD and pulmonary function and point to the potential use of respiratory center drive to identify early PD.