November 21st 2024
Currently, chemotherapy remains a common treatment for biliary tract cancers, which have a limited survival rate.
Barriers to Recruiting ED Patients With Advanced Cancer for Palliative Care
July 25th 2017Patient refusal, symptom burden, and diagnostic disparities were identified as some of the most common barriers encountered when recruiting patients with advanced cancer for palliative treatment in the emergency department (ED).
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Immune-Cell Numbers Determine Combination Immunotherapy Response in Melanoma Patients
July 25th 2017The Journal of Clinical Investigation Insight recently published a study that analyzed 112 different melanoma tumors in attempt to correlate partially exhausted cytotoxic lymphocytes (peCTLs) and regulatory T lymphocyte (Treg) levels with response to combination immunotherapy.
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Brazilian Study Queries: Is NGS Cost-Effective in Advanced Lung Cancer?
July 22nd 2017In a study presented at the 2017 American Society of Clinical Oncology Annual Metting, researchers from the Brazilian Cancer Foundation and the Brazilian National Cancer Institute evaluated the cost-effectiveness of a unique exam using next-generation sequencing versus other routine tests.
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Adjuvant Chemotherapy Reduces Cost, Improves Survival in NSCLC Post-Surgery
July 22nd 2017Including adjuvant chemotherapy in the postsurgical treatment plan in patients with non—small cell lung cancer (NSCLC) improves survival and is cost-effective compared with surgical resection alone, according to analysis results presented at the 2017 American Society of Clinical Oncology Annual Meeting.
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CT-P6, a Trastuzumab Biosimilar, Shares the Safety and Efficacy Profile of Its Reference
July 21st 2017CT-P6, a proposed trastuzumab biosimilar, is safe and effective as a neoadjuvant treatment in HER2—positive early breast cancer, according to research presented at the 2017 American Society of Clinical Oncology Annual Meeting.
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Research Demonstrates Efficacy and Safety of Trastuzumab Biosimilar SB3
July 21st 2017Research presented at the 2017 American Society of Clinical Oncology Annual Meeting showed that SB3, a proposed biosimilar to trastuzumab, has comparable efficacy, safety, immunogenicity, and pharmacokinetics to the reference product based on the breast pathological complete response.
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Switching Study Reports Equivalence Between Filgrastim, Biosimilar in Breast Cancer
July 21st 2017After switching studies, research in patients with breast cancer receiving neoadjuvant myelosuppressive chemotherapy has found clinical equivalence between filgrastim and its biosimilar, according to results presented at the 2017 Annual Meeting of the American Society of Clinical Oncology.
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ASCO Study Finds Shift in Diagnosis Stage for Several Cancers Following ACA Implementation
July 21st 2017The diagnosis of stage I disease increased for female breast cancer, colorectal cancer, and lung cancer following implementation of the Affordable Care Act (ACA), according to research presented at the 2017 American Society of Clinical Oncology Annual Meeting in Chicago.
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Examining How Online Patient-Reported Outcomes Make a Difference in Cancer Care
July 21st 2017In a webinar hosted by Carevive, researcher Ethan Basch, MD, MSc, discussed the findings of his recent study linking electronic patient-reported outcomes (PROs) to better survival outcomes for patients with cancer.
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Do We Have Adequate Surveillance in Cancer Care?
July 20th 2017A poster discussion session at the 2017 Annual Meeting of the American Society of Clinical Oncology led by Katherine Van Loon, MD, MPH, examined retrospective surveillance data in 3 cancers: non—small cell lung cancer, head and neck cancer, and colorectal cancer.
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Physician, Regulatory, and Payer Perspectives on the Value of Real-World Data
July 20th 2017A kickoff session on the first day of the 2017 American Society of Clinical Oncology Annual Meeting in Chicago turned in to a lively discussion on ensuring that the data used to inform patient care and create healthcare policies hold value, which could entail foraging real-world data captured in health records.
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According to outcome results presented at a plenary session at the 2017 American Society of Clinical Oncology Annual Meeting, patients receiving routine outpatient chemotherapy for metastatic solid tumors who self-reported 12 common symptoms via tablet computers experienced an overall survival benefit over those who received usual care.
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Ibrutinib vs No Consolidation Are Being Compared Following Autologous HSCT in IRONCLAD Trial
July 20th 2017A poster session at the 2017 American Society of Clinical Oncology Annual Meeting presented the trial details of IRONCLAD, a randomized phase 3 study of ibrutinib versus no consolidation following autologous hematopoietic stem cell transplantation for activated-B-cell subtype relapsed diffuse large B-cell lymphoma.
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Study Queries Cost—Quality Tradeoff in Narrow Oncology Provider Networks
July 20th 2017Researchers at the University of Pennsylvania have recognized that narrow provider networks are quite likely to exclude National Cancer Institute—Designated Cancer Centers or National Comprehensive Cancer Network Cancer Centers, which could prevent patient access to high-quality cancer care.
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Nivolumab, Alone or With Ipilimumab, Met the Disease Control Rate in Malignant Pleural Mesothelioma
July 19th 2017In a late-breaking abstract at the 2017 American Society of Clinical Oncology Annual Meeting, researchers presented an interim analysis of a randomized phase 2 trial of second- or third-line nivolumab, with or without ipilimumab, in patients with second- or third-line malignant pleural mesothelioma.
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Three Months of Oxaliplatin-Based Adjuvant Therapy Noninferior to 6 Months in Stage III Colon Cancer
July 19th 2017The International Duration Evaluation of Adjuvant chemotherapy (IDEA) collaboration found evidence to support the noninferiority of 3 versus 6 months oxaliplatin-based adjuvant therapy for capecitabine plus oxaliplatin for patients with stage III colon cancer.
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Fas Biomarker Can Predict Response to Second-Line Therapy for Advanced Soft Tissue Sarcoma
July 19th 2017In a study performed by the Grupo Español de Investigación en Sarcomas, Fas biomarker detection showed value in predicting progression-free and overall survival after trabectedin administration to patients with advanced soft tissue sarcoma.
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HPV Vaccination May Lower Prevalence of Oropharyngeal Cancers in Young Adults
July 19th 2017The incidence of human papilloma virus (HPV)-positive oropharyngeal cancer can be reduced with a prophylactic vaccine, according to a collaborative study that was presented at the 2017 American Society of Clinical Oncology Annual Meeting in Chicago.
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Trabectedin and Lurbinectedin Effective in BRCA2-Associated Metastatic Breast Cancer
July 18th 2017An interim analysis of two phase 2 trials, reported in a poster session at the 2017 American Society of Clinical Oncology Annual Meeting, has found that trabectedin and lurinectedin demonstrated remarkable activity as single agents in BRCA2-associated metastatic breast cancer.
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