Inflammation

A comparison of claims-based asthma risk predictors in a national sample of children with Medicaid determines accuracy and informs risk predictor choice.

The trend was true when investigators used body mass index to classify weight, and when measures such as relative body mass index and percentage of body fat were used.

The study showed children with thalassemia had a greater risk of both atopic and non-atopic asthma.

As many as 4% of population-level asthma cases could be attributed to secondhand smoke, the study suggests.

The analysis found 20% of people with asthma, emphysema, or chronic bronchitis also have depression.

Sold under the name Dupixent, dupilumab is a biologic that inhibits interleukin (IL)-4 and IL-13, which are key drivers of the type 2 inflammation that plays a major role in asthma, chronic rhinosinusitis with nasal polyps, atopic dermatitis, and eosinophilic esophagitis.

A recent article describes the many challenges faced by patients with mast cell disorders, which involve unpredictable, disabling symptoms that interfere with daily life activities.

Michael E. Wechsler, MD, a pulmonologist at National Jewish Health, discusses the conditions that can develop as a result of abnormal eosinophilic activity.

It is the third set of warnings for certain Janus kinase (JAK) inhibitors due to the risk of heart attack or stroke, cancer, blood clots, and death.

Switching patients with asthma to a biologic medication purely because that patient is not adherent to inhaled medications gets in the way of a physician's goal of being good stewards of patient care and finances, said William "Andy" Nish, MD.

Most patients said they had received instruction on how to use their inhalers from a pharmacist or physician, but only 21% said they had received instruction from both.

Nearly 9 in 10 children given intravenous (IV) magnesium for refractory asthma ended up being admitted to the hospital, but new research suggests that may be partly due to a lack of clarity about the therapy’s safety profile.

Many intrinsic and extrinsic factors hinder primary health care professionals from identifying a patient as having occupational asthma.

Getting vaccinated is important to protect yourself, your family, and your community, says William "Andy" Nish, MD, an allergist and immunologist at Northeast Georgia Physicians Group.

Although body weight affected pharmacokinetics, the investigators said dosing adjustments based on weight were not warranted.

William "Andy" Nish, MD, an allergist and immunologist at Northeast Georgia Physicians Group, discusses the factors that influence whether patients with asthma should be prescribed a biologic therapy.

Data suggest asthma exacerbations dropped for children and adolescents during the pandemic, and most families chose to use telehealth services when available.

Viral infections can induce asthma exacerbations, but a report finds the inflammation itself can also have an impact on the infection.

When particulate matter concentrations were high, patients were more likely to experience asthma exacerbations and likely were also more likely to have reactions to house dust mites.

The more often a patient used systemic corticosteroids, the higher their risk of moderate or severe COVID-19 and all-cause mortality, the study found.

New research based on real-world data largely aligns with the scientific literature, although one monoclonal antibody—dupilumab—stood out for its very low risk.

Pediatric patients with atopic dermatitis (AD) often vary in disease severity and it can be difficult to assess how much of a topical therapy is needed, said Lawrence F. Eichenfield, MD, chief of pediatric and adolescent dermatology at Rady Children's Hospital-San Diego.

A handful of systemic therapies can be prescribed off label to effectively treat atopic dermatitis (AD), but investigators said a biologic option may be best for many patients.

Highlighting the latest inflammation-related news reported across MJH Life Sciences™.

A panel of health care professionals reviewed published literature to develop a recommendation guide to advise providers on best practices when considering vaccinations for children with atopic dermatitis (AD) on dupilumab.

Patients with atopic dermatitis (AD) benefit from extensive patient education. A new report suggests group-based sessions are preferred to individual educational sessions or fun activities.

Existing research has focused on skin symptoms, but a new study looks for alterations in the blood associated with moderate-to-severe atopic dermatitis.

A new report shows work-related quality of life in general—and also in terms of physical and mental/emotional health—improved when patients began treatment for atopic dermatitis.

Now that racial and ethnic disparities of atopic dermatitis prevalence among children have been confirmed, the next step in research will be to discover the reasons why those disparities exist, said Jonathan Silverberg, MD, PhD, MPH.

Children with severe atopic dermatitis, in particular, were less likely than a control group to complete education at all levels, from basic compulsory education to postgraduate education.