COPD

A recent study determined that patients with chronic obstructive pulmonary disease (COPD) and non-small cell lung cancer (NSCLC) had similar tumor microenvironment, but higher tumor infiltrating lymphocytes (TIL) exhaustion, than patients without COPD. The use of an anti-programmed cell death-1 (PD-1) antibody, nivolumab, was also demonstrated to be effective in this population.

Some patients with chronic obstructive pulmonary disease (COPD) experience a sudden worsening of their symptoms that require additional treatment—also known as acute exacerbation of COPD (AECOPD). A recent study, which investigated whether readmissions of patients with severe AECOPD varied according to the bacterium or virus identified, found that P. aeruginosa identification is associated with a higher readmission rate in patients.

Previous phase 3 studies have demonstrated the efficacy of nebulized glycopyrrolate inhalation solution (GLY) for treating patients with chronic obstructive pulmonary disease (COPD). In a recent study, researchers conducted a secondary analysis and found that nebulized GLY demonstrated efficacy and was well tolerated for up to 48 weeks in subjects with COPD with or without background long-acting beta2-agonist (LABA).

Patient adherence to medication is a complex issue, particularly so for patients with chronic obstructive pulmonary disease (COPD). A recent study finds that adherence is related to need perception and to the functional severity of the disease.

Patients with chronic obstructive pulmonary disease (COPD) often have a significant disease burden that is particularly associated with the peak incidence of exacerbation events during winter months. A review assessed previous population studies that evaluated the impact of seasonality in COPD, emphasizing the importance of understanding how all factors impact patients and where interventions can be targeted.

Older age, dyspnea, longer duration of illness, comorbidities, and use of oxygen hurt quality of life for those with chronic obstructive pulmonary disease.

A Mayo Clinic team critiqued the 2018 update to the Global Initiative for Chronic Obstructive Lung Disease guidelines, recommending several changes to the next update.

A study found that testosterone replacement therapy reduced the risk of respiratory hospitalizations in men with chronic obstructive pulmonary disease (COPD).

A phase 2 clinical trial of a surgical procedure called targeted lung denervation to open blocked airways in patients with chronic obstructive pulmonary disease (COPD) showed that it reduced problems associated with the disease.

There is an increased need for potential biomarkers that can identify patients with chronic obstructive pulmonary disease (COPD) who will benefit from treatment involving inhaled corticosteroids (ICS). According to a recent study, the 2% threshold for blood eosinophils could accurately predict ICS treatment response in patients with COPD, but the risk of pneumonia was increased.

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a recent genome study.

Telerehabilitation (TR), defined as telecare that involves supervised online exercise sessions for patients with chronic obstructive pulmonary disease (COPD), is beneficial for symptom relief, physical function, and quality of life. A recent study found that specific attention toward the involvement of health professionals in the decision process combined with education and skill training is essential to support the successful implementation of TR.

Early hospital readmissions for patients with asthma and chronic obstructive pulmonary disease (COPD) represent a major economic burden within the healthcare system and recent research found that comorbid chronic rhinitis is significantly associated with 30-day asthma and COPD related readmissions

Patients with chronic obstructive pulmonary disease (COPD) still rely on their healthcare providers as the source of primary information about their disease but about a third will bring information from the internet to appointments to discuss, and prioritize information about symptom control, a recent online survey reported.

Patients with chronic obstructive pulmonary disease (COPD) with a history of at least 1 emergency department visit or hospitalization are eligible for a new digital health initiative announced by Anthem Blue Cross and Blue Shield for its Ohio Medicare Advantage (MA) plans, where it will cover digital sensors from Propeller Health.

Long-term exposure to secondhand smoke (SHS) during childhood increases the risk of chronic obstructive pulmonary disease (COPD) death in adulthood, according to a new study.

Patients with chronic obstructive pulmonary disease and who have other comorbid conditions are undertreated when hospitalized for exacerbations, study finds.

A study that sought to replicate the effects of vaping on lung cells found that vapor from e-cigarettes boosts the production of inflammatory chemicals and disables key protective cells in the lung that engulf potentially harmful particles. Some of the effects were similar to those seen in regular smokers and people with chronic obstructive pulmonary disease.

Lifestyle factors and individual characteristics, rather than air pollution, explain which women with asthma go on to develop chronic obstructive pulmonary disease (COPD), resulting in asthma and COPD overlap syndrome (ACOS), according to a new study published in the Annals of the American Thoracic Society.

Researchers investigating the factors associated with hospital mortality in patients requiring intensive care unit admission for acute exacerbations of chronic obstructive pulmonary disease found that patient age, requirement for invasive mechanical ventilation, and illness severity were associated with poor patient outcomes.

Patients with chronic obstructive pulmonary disease who work are costly to their employers in both direct and indirect costs and have greater productivity losses, according to a recent study.

The use of inhaled vaporized cannabis neither improved nor worsened exercise performance and activity-related breathlessness for patients with advanced chronic obstructive pulmonary disease, according to a recent trial published in the Annals of the American Thoracic Society.

Researchers recently found that the use of a standardized electronic health system–based order set to manage acute exacerbations of chronic obstructive pulmonary disease was linked to a decreased reduction in steroid dose and length of stay in the hospital.

An FDA advisory committee voted 16-3 against recommending GlaxoSmithKline’s mepolizumab (Nucala) as an add-on treatment to inhaled corticosteroid-based maintenance treatments to reduce flare-ups in patients with chronic obstructive pulmonary disease (COPD).

Researchers recently aimed to develop a predictive model to identify patients at risk of developing severe COPD exacerbations, finding that for every 2 patients identified to be at risk of severe flare-up of disease, 1 patient may experience a severe exacerbation.

Recent research has suggested that small airway disease is a pathological feature in mild and moderate chronic obstructive pulmonary disease (COPD) and that early intervention for disease modification may be required in these patients.

Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) who have short telomeres, a biomarker of aging, are more likely to have a worse quality of life and have a higher risk of exacerbations and death, according to a recent study, but daily azithromycin may help.

A recent study found that patients with chronic lung conditions such as chronic obstructive pulmonary disease are more likely to be physically active when they have regular contact with healthcare professionals, support from peers, and access to organized exercise sessions.

Breathing in additional oxygen improves the function of blood vessels in the brains of people with chronic obstructive pulmonary disease (COPD), according to recent research.