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Reflections on 2024’s Progress in R/R CLLPanelists discuss how the relapsed/refractory chronic lymphocytic leukemia treatment landscape evolved significantly in 2024 with expanded Bruton tyrosine kinase inhibitor options, growing real-world evidence for newer agents, and emerging combination strategies, while expressing optimism for future advances in personalized therapy approaches and novel drug development.
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Moving Beyond Steroids to a New Era in Chronic Hand Eczema Treatment: Raj Chovatiya, MD, PhD, MSCIRaj Chovatiya, MD, PhD, MSCI, describes how delgocitinib offers a long-term solution for chronic hand eczema, transforming treatment beyond traditional corticosteroids.
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Limited English Proficiency, Cardiovascular Risk Factors, Cardiovascular Disease, and In-Hospital COVID-19 OutcomesThis study evaluated whether limited English proficiency modifies the association between cardiovascular risk factors or cardiovascular disease and outcomes in patients hospitalized with COVID-19.
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The Biosimilar Shift: Trending Infliximab Biosimilar Utilization and Associated Cost Savings for Commercial InsuranceInfliximab biosimilars created price competition causing insurance claims costs for infliximab originator and infliximab biosimilars to decrease, generating significant savings to the health care system.
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Optimizing the Management of TRDDrs Steven Levine, Patricia Ares-Romero, Samuel Nordberg, Martin Rosenzweig, and Carrie Jardine share insight on the future treatment landscape for TRD.
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Final Panelist Thoughts on the Management of Pulmonary Arterial HypertensionPanelists discuss how the future of PAH treatment looks promising with potential for disease remission through reverse remodeling agents, emphasizing the need for continued research focus on patients with other forms of pulmonary hypertension and those with significant comorbidities.
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Care Fragmentation Predicts 90-Day Durable Ventricular Assist Device OutcomesThis analysis evaluates the relationship between hospital care delivery network fragmentation and in-hospital and 90-day outcomes. These networks may be novel targets for improving outcomes.
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Impact of COVID-19 Pandemic on Accessibility of Taiwanese Medical CareThe COVID-19 pandemic disrupted access to routine medical care in community populations in Taiwan. The unmet needs should be emphasized as normal life resumes.
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Frameworks for Advancing Health Equity: Food as MedicineLearn about how Allegheny Health Network's "Food as Medicine" initiative tackles food insecurity and enhances health through personalized nutrition support.
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Psoriasis Treatment Center of New Jersey Reports Positive Results for Tapinarof in Psoriasis TrialIn this study, 52% of adult patients achieved the treat-to-target goal of 1% BSA or less within 3 months of incorporating tapinarof cream into their biologic regimen.
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Addressing Unmet Needs in Lung Cancer to Optimize Precision Medicine and Immunotherapy: Angel Qin, MDAngel Qin, MD, identified the critical role of immunotherapy timing and shared decision-making in small cell lung cancer while also addressing the need for more broadly applicable treatments and personalized care.
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Care Coordination Engagement Patterns in Long-Term PatientsCare coordination engagement increases over time in long-term high-cost, high-need patients, with no identifiable data-driven times for when to initiate patient care de-escalation.
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Screening for Health Literacy, Social Determinants, and Discrimination in Health PlansThis study provides insight on the experiences of patients of a national health plan with 2 structural determinants of health—health care discrimination and health literacy—and how those interact with social determinants of health and patient demographics.
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Elinzanetant Shows Strong 52-Week Safety for Vasomotor Symptoms: James Simon, MDUS safety data show that elinzanetant caused few adverse events and no new liver-related concerns in women, James Simon, MD, explains.
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US Cost-effectiveness and Budget Impact of Point-of-Care NAAT for StreptococcusThis study evaluates the cost-effectiveness and budget impact to US payers of point-of-care nucleic acid amplification tests (NAAT) for group A streptococcus.
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Researchers Propose Model to Replicate Patient Experience in Artificial Pancreas SystemA methodology to monitor patient-in-the-loop modes and faults was examined using a hybrid automata model that was able to replicate patient’s real-life operation modes.
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Real-world HIV Diagnostic Testing Patterns in the United StatesThis retrospective study evaluated real-world implementation of the updated CDC HIV algorithm in a large US laboratory.
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Growth of Electronic Consultations in the Veterans Health AdministrationThis study evaluates the growth in electronic consultation use over the first 7 years after its implementation across the entire Veterans Health Administration system.
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Ensuring Access to Health Care by FQHCs as States Reopen Amid COVID-19Federally qualified health centers (FQHCs) must focus on enhancing the nonemergency medical transportation Medicaid benefit to improve patient access during the coronavirus disease 2019 (COVID-19) emergency as states reopen.
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Considerations to Increase Rates of Breast Cancer Screening Across PopulationsAuthors from the Community Oncology Alliance and Avalere Health present data that show breast cancer screening rates recovered more slowly among some racial/ethnic groups following on the onset of the COVID-19 pandemic.
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Tafasitamab Approval Expands Chemotherapy-Free Treatment Options for R/R Follicular Lymphoma: Christina Poh, MDChristina Poh, MD, of City of Hope National Medical Center, highlights the benefit of tafasitamab in improving progression-free survival for heavily pretreated patients with relapsed or refractory (R/R) follicular lymphoma.
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Advanced Care at Home at Scale in an Integrated Health Care SystemAdvanced care at home (otherwise known as hospital at home) can be scaled and provide care for a sizable portion of a hospital’s inpatient census, creating hospital capacity in an integrated delivery system.
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Contemporary Care Patterns in the Management of Small Renal MassesAn investigation of management patterns after initial radiographic diagnosis of small renal masses showed that early urologist referral was associated with guideline-concordant care.
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Abelacimab Shows Potential to Shift the Standard of Care in AFibResults from the AZALEA-TIMI 71 phase 2 trial showed great promise for abelacimab to transform care for high-risk patients with atrial fibrillation.
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Development and Validation of the COVID-19 Hospitalized Patient Deterioration IndexThe authors developed and validated an accurate, well-calibrated, easy-to-implement COVID-19 hospitalized patient deterioration index to identify patients at high or low risk of clinical deterioration.
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Perspectives on Nonmedical Switching and the COVID-19 Pandemic: A Narrative ReviewThis review describes the impact of nonmedical switching of biologic therapies on US patients and providers, with a focus on switching to in-class alternatives.
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Improving System-Based Tobacco Cessation in a Community Health ClinicThis case study demonstrates how system-based tobacco cessation was enhanced in a community clinic.
