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Sequencing Therapies and Using the Most Effective Options First
Experts discuss the complexities of treatment sequencing in cancer therapy, emphasizing the importance of using the best therapies upfront for optimal outcomes.
EP: 1.Understanding EGFR Mutations and First-Line Treatment
EP: 2.Overcoming Resistance Mechanisms and Addressing Unmet Needs
EP: 3.Impact of Recent Approvals and Novel Mechanisms
EP: 4.CNS Penetration and Efficacy of Emerging Therapies
EP: 5.Managing Adverse Events and Integrating Amivantamab Plus Lazertinib
EP: 6.Sequencing Therapies and Using the Most Effective Options First
Panelists discuss how sequencing strategies influence long-term disease control and patient survival in EGFR-positive non–small cell lung cancer (NSCLC). They explore the advantages of initiating treatment with the most efficacious agents upfront, weighing this against the potential loss of future options. The conversation examines resistance evolution, patient-specific factors, and clinical evidence supporting early use of potent targeted combinations. Ultimately, the panel underscores the trend toward frontloading the most effective treatments to achieve deeper, longer-lasting responses.
Preventing Tomorrow’s High-Cost Claims: The Rising-Risk Patient Opportunity in Medicaid
November 6th 2025For Medicaid care management, focusing on rising-risk patients is more effective than targeting high-cost claimants, whose spending tends to decrease over time due to regression to the mean.
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