Sitting time was responsible for 3.8% of all-cause mortality in 54 countries studied, and eliminating sitting time could increase life expectancy by 0.20 years in those nations.
Reducing the amount of time spent sitting plays an important role in promoting an active lifestyle, which is an important aspect of preventing premature mortality worldwide, according to a new analysis of data from 54 countries. The study was published in the American Journal of Preventive Medicine.
Brazilian and Spanish researchers led by Leandro Fornias Machado de Rezende, MSc, found that sitting time was responsible for 3.8% of all-cause mortality (about 433,000 deaths per year in these countries), and they concluded that eliminating sitting time would increase life expectancy by 0.20 years in those nations. The researchers believe their new estimates about reducing sitting time might be helpful to policy makers considering the impact of sedentary behavior on public health.
All-cause mortality due to sitting time was higher in the countries from the Western Pacific region, followed by European, Eastern Mediterranean, American, and Southeast Asian countries.
The burden of disease attributable to inactivity has been estimated to be responsible for 6% to 9% of total deaths worldwide. Some researchers argue that excessive time spent sitting may be harmful to health regardless of whether people meet recommended guidelines of moderate-to-vigorous physical activity. They suggest that rather than focusing only on activities of at least moderate intensity, replacing sitting time with standing or light physical activity may also provide significant public health benefits.
This study’s goal was to estimate the population attributable factor (PAF) for all-cause mortality associated with time spent sitting. PAF is a measure epidemiologists use to quantify and summarize the public health burden related to one factor—in this case, time spent sitting—and how much a certain outcome (in this study, all-cause mortality) can be reduced by eliminating that factor.
The researchers found that for the adults in the 54 countries studied, the weighted mean sitting time across countries was 4.7 hours/day. Even modest reductions in sitting time, such as a 10% reduction in mean sitting time or a 30-minute absolute decrease in daily sitting time, could have an instant impact in all-cause mortality (0.6%) in the countries that were evaluated. Bigger changes, such as a 50% decrease or 2 fewer hours of sitting, would mean at least 3 times fewer deaths than the 10% or 30-minute sitting time reduction.
FDA Approves Expanded Indication of Eculizumab for Pediatric Generalized Myasthenia Gravis
March 15th 2025The FDA first approved eculizumab for use in adult patients with generalized myasthenia gravis in 2017, before expanding the indication to include pediatric patients who are 6 years or older and positive for antiacetylcholine receptor antibodies.
Read More
Navigating Sport-Related Neurospine Injuries, Surgery, and Managed Care
February 25th 2025On this episode of Managed Care Cast, we speak with Arthur L. Jenkins III, MD, FACS, CEO of Jenkins NeuroSpine, to explore the intersection of advanced surgical care for sport-related neurospine injuries and managed care systems.
Listen
The Impact of Cost Sharing on High-Value Care
March 14th 2025Michael Chernew, PhD, professor of health care policy and director of the Healthcare Markets and Regulation Lab, Harvard Medical School, shares how cost-sharing policies shape access to critical health care services and influence value-based insurance design.
Read More
Varied Access: The Pharmacogenetic Testing Coverage Divide
February 18th 2025On this episode of Managed Care Cast, we speak with the author of a study published in the February 2025 issue of The American Journal of Managed Care® to uncover significant differences in coverage decisions for pharmacogenetic tests across major US health insurers.
Listen
Oz Confirmation Hearing Probes Vision for Medicaid but Coalesces Around Well-Being
March 14th 2025Mehmet Oz, MD, the nominee to lead CMS under the Trump administration, testified in a confirmation hearing before the Senate Finance Committee, where he found common ground on improving outcomes through healthier lifestyle choices but encountered repeated questions on potential Medicaid cuts.
Read More