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Patient Factors Influencing Antibiotic Selection in Uncomplicated UTIs

Opinion
Video

Panelists discuss how fluoroquinolones are generally reserved for uncomplicated urinary tract infections (UTIs) only when first-line options are contraindicated or pathogen resistance is confirmed, with treatment duration ranging from single-dose fosfomycin to 3 to 5 days for most antibiotics and 7 to 10 days for nitrofurantoin, noting shorter regimens typically achieve 85% to 95% adherence rates compared with 60% to 75% for longer courses, significantly affecting treatment success, particularly when patient factors such as adverse effects, dosing complexity, and lifestyle disruptions are considered.

Video content above is prompted by the following:

  • In which clinical scenarios would the use of other therapies, such as fluoroquinolones, be recommended for treating uncomplicated UTIs, and what factors guide the decision to choose these over preferred treatments?
  • How does the duration of therapy differ across treatment options, and how does this affect patient adherence rates and treatment success?
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