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Identifying and Navigating Challenges Associated With Clinical Pathways in the Treatment of HCC

Opinion
Video

Ryan Haumschild, PharmD, MS, MBA, drives an expert discussion focused on challenges associated with clinical pathway utilization in treating patients with HCC.

The panel discussion focused on the complexities surrounding the development and implementation of clinical pathways in the context of hepatocellular carcinoma (HCC) treatment. Mohamed Salem, MD, highlighted the importance of ensuring that the pathways developed are applicable to a diverse range of practices and centers, emphasizing the need for a more generalized approach. Challenges regarding the integration of cutting-edge research into established pathways were discussed, with Ghassan Abou-Alfa, MD, MBA, emphasizing the importance of basing updates on relevant data while maintaining an open, transparent, and democratic process.

The speakers acknowledged the potential conflicts of interest that could arise when experts involved in research attempt to influence the content of clinical pathways. Dr Abou-Alfa advocated for transparency and an open discussion to ensure that the decision-making process remains driven by objective data rather than individual preferences. The critical role of clinical trials and expert insights was emphasized, highlighting the need to integrate a shared decision-making framework to benefit patients effectively.

Additionally, the panel addressed the challenges associated with incorporating non–FDA approved treatments into clinical pathways, emphasizing the importance of balancing the need for timely updates with the requirement for vetted and approved treatments. Dr Salem’s insight underscored the necessity of navigating these challenges and finding a balance between prompt integration and regulatory approval.

Overall, the discussion shed light on the multifaceted nature of developing clinical pathways and highlighted the significance of aligning them with the latest research data and guidelines. The emphasis on transparency, data-driven decision-making and the collective expertise of the medical community emerged as critical themes throughout the conversation, ultimately underscoring the goal of optimizing patient outcomes and ensuring the highest standard of care for individuals with HCC.

Video synopsis is AI-generated and reviewed by AJMC editorial staff.

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