Highlights from last week include President Trump's executive orders, the FDA approval of esketamine nasal spray for depression, mental health access through Medicaid Managed Care, the impact of travel time on surgical outcomes, and life expectancy disparities.
In his first actions as the 47th president, Donald Trump reversed several Biden-era health policies, including rescinding Affordable Care Act (ACA) enrollment expansions, withdrawing from the World Health Organization (WHO), and halting drug pricing initiatives. Trump's rollback of ACA provisions, which had significantly increased enrollment and improved health outcomes for low-income individuals, threatens coverage and financial benefits for vulnerable populations. His elimination of 3 Center for Medicare and Medicaid Innovation (CMMI) drug pricing models halts planned reforms targeting cost reductions for generics and innovative therapies. The WHO withdrawal drew backlash for undermining global health surveillance, while the dismantling of pandemic preparedness efforts and diversity, equity, and inclusion (DEI) initiatives raised alarm among experts advocating for health equity.
In this episode of Managed Care Cast, Allison Ju-Chen Hu, PhD, a postdoctoral associate at Weill Cornell Medicine, discusses her study, "Medicaid Managed Care Network Adequacy Standards and Mental Health Care Access." The research explores how quantitative network adequacy standards—policies designed to ensure sufficient provider availability—impact mental health care access for adult Medicaid enrollees, particularly those with mental health conditions.
A new study reveals a staggering 20.4-year gap in life expectancy across racial, ethnic, and geographic lines in the US by 2021, exacerbated by structural inequities and the COVID-19 pandemic. Expanding on the Eight Americas study, researchers identified 10 distinct "Americas" based on demographics and socioeconomic factors, showing widening disparities since 2000. American Indian and Alaska Native (AIAN) populations in the West faced steep declines, while gains for Black populations stalled, and Latino Americans experienced regional disparities. The pandemic deepened these inequities, particularly for socially and economically disadvantaged groups.
The FDA approved esketamine (Spravato) nasal spray as the first monotherapy for adults with major depressive disorder (MDD) who have not responded to at least 2 oral antidepressants following a priority review. Clinical trials showed rapid improvement in depressive symptoms within 24 hours and sustained benefits at 4 weeks, with 22.5% of patients achieving remission compared with 7.6% on placebo. The therapy demonstrated superior efficacy to quetiapine for TRD in 2023, increasing remission likelihood by 54%. Available in 77 countries and administered under a Risk Evaluation and Mitigation Strategy Program, esketamine offers a faster-acting alternative to traditional antidepressants, which often take weeks to work.
The significant impact of prolonged travel time on emergency care outcomes was observed in new research, surpassing the influence of rurality alone. Analyzing data from over 190,000 patients in Florida and California, researchers found that longer travel times were associated with more severe disease presentation, higher surgical intervention rates, increased hospital admissions, longer stays, and greater costs. While rurality did not independently correlate with disease complexity, rural patients with extended travel times faced higher risks. The findings underscore the need for metrics and interventions to address travel barriers and ensure timely access to emergency care, particularly in underserved areas.
AI in Health Care: Balancing Governance, Innovation, and Trust
September 2nd 2025In this conversation with Reuben Daniel, associate vice president of artificial intelligence at UPMC Health Plan, we dive into how UPMC Health Plan builds trust with providers and members, discuss challenges of scaling AI effectively, and hear about concrete examples of AI's positive impact.
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Rideshare Cuts Colon Cancer Deaths, Saves Costs After Abnormal FIT, Study Finds
September 4th 2025A study finds that $100 rideshare rides for follow-up colonoscopy after fecal immunochemical test (FIT) doubled completion rates, reduced colorectal cancer (CRC) deaths, and lowered health care costs.
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Infertility Coverage Boosts ART Use and Pregnancy Success: Richard A. Brook, MS, MBA
August 26th 2025In this episode, Richard A. Brook, MS, MBA, discusses his study showing that infertility treatment coverage increases assisted reproductive technology (ART) use and improves pregnancy outcomes.
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Racial, Ethnic Disparities May Impact Age Differences at First Heart Failure Hospitalization
September 4th 2025Social determinants of health were associated with a younger age of first hospitalization for heart failure in Black and Hispanic patients when compared with Asian and White patients.
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