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Exploring the Pathophysiology and Diagnosis of Bronchiectasis
A panelist discusses how bronchiectasis involves a vicious cycle of airway damage, where neutrophilic inflammation leads to bronchial wall destruction and dilation, while explaining that diagnosis relies primarily on high-resolution CT imaging showing bronchial wall thickening and dilated airways, distinguishing it from the emphysematous changes seen with chronic obstructive pulmonary disease (COPD).
Video content above is prompted by the following:
- Can you please describe the pathophysiology of bronchiectasis, specifically the role of neutrophilic inflammation?
- How is bronchiectasis diagnosed in clinical practice, and how is it differentiated from other pulmonary diseases like COPD?
Abortion in 2025: Access, Fertility, and Infant Mortality Updates
February 20th 2025While Republican state-led efforts aim to increase restrictions to abortion care and access to mifepristone and misoprostol in 2025, JAMA authors join the conversation with their published research and commentary.
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Ovarian Cancer Outcomes Linked to Preoperative Immunonutritional Status
February 18th 2025In patients with early-stage ovarian cancer, a high prognostic nutritional index improved survival, while a high systemic immune-inflammation index worsened it. In advanced stages, both affected overall survival but not progression-free survival.
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