Although cost-effectiveness analysis has not been a formal part of cardiology clinical guidelines until recently, it has "always been the elephant in the room," said Mark Hlatky, MD, professor of health research and policy and professor of cardiovascular medicine at Stanford University.
Although cost-effectiveness analysis has not been a formal part of cardiology clinical guidelines until recently, it has "always been the elephant in the room," said Mark Hlatky, MD, professor of health research and policy and professor of cardiovascular medicine at Stanford University.
Transcript (slightly modified for readability)
How much does cost effectiveness come into consideration when creating and utilizing cardiology clinical guidelines?
Cost-effectiveness analysis has not been formally part of clinical guidelines until just recently. I think it's always been the elephant in the room, where people understood that if it is a costly therapy, we need to take into account whether it was really providing any value. But there was no formal mechanism for doing that. The American College of Cardiology and the American Heart Association recently adopted the idea that we would, in fact, put value grades in for therapies that were judged to be highly effective therapies. We also try to assess their value and incorporate some recognition of the value statement into our guidelines. That's going to happen going forward.
In what ways can cost effectiveness be better utilized when creating new cardiology clinical guidelines?
One of the things that we have an issue for is we are evidence-based and we're not going to be commissioning models of developing things specifically to support the guidelines. So we're going to have to take what's been done already. I think ISPOR and other organizations can be extremely helpful in helping us understand what good studies are and having a way to grade the evidence on this. I think economic evaluations are very complicated sometimes and very difficult to assess and I think we need to figure out ways to make them simpler and to make them credible so they can go and support the guideline.
Could On-Body Delivery of Isatuximab Bring More Competition to Anti-CD38 Myeloma Treatment?
June 6th 2025Results for IRAKLIA show noninferiority for Sanofi's on-body delivery system for isatuximab, compared with IV administration. Patients overwhelmingly preferred the hands-free delivery option.
Read More
Laundromats as a New Frontier in Community Health, Medicaid Outreach
May 29th 2025Lindsey Leininger, PhD, and Allister Chang, MPA, highlight the potential of laundromats as accessible, community-based settings to support Medicaid outreach, foster trust, and connect families with essential health and social services.
Listen
ICS Use Tied to Fewer Exacerbations in Patients With Bronchiectasis and Elevated Blood Eosinophils
June 6th 2025Inhaled corticosteroid (ICS) use was common among patients with bronchiectasis and was associated with reduced exacerbations and hospitalizations in those with elevated blood eosinophil counts.
Read More
Real-World Data Support Luspatercept vs ESAs for Anemia in Lower-Risk MDS
June 5th 2025Patients with myelodysplastic syndrome (MDS) who received luspatercept showed greater hemoglobin gains and transfusion independence compared with erythropoiesis-stimulating agents (ESAs) in a real-world analysis.
Read More
At EHA 2025, Hematology Discussions Will Stretch Across Lifespans and Locations
June 5th 2025The 2025 European Hematology Association (EHA) Congress, convening virtually and in Milan, Italy, from June 12 to June 15, 2025, will feature a revamped program structure for the meeting’s 30th anniversary while maintaining ample opportunities to network, debate, and absorb practice-changing findings in hematology and oncology.
Read More