A panelist discusses how antibody-drug conjugates like mirvetuximab should be sequenced in platinum-resistant ovarian cancer, recommending it as first-line therapy for folate receptor alpha–high tumors due to higher response rates when used earlier.
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Sequencing Antibody-Drug Conjugates in Platinum-Resistant Ovarian Cancer
Panelist Introduction
AJMC Insights Series features Kathleen Moore, MD, MS, a gynecologic oncologist and expert in ovarian cancer treatment. Dr Moore discusses various aspects of novel therapies for ovarian cancer treatment across 4 interview segments.
Expert Background
Kathleen Moore, MD, MS
Key Themes:
Notable Insights:
Dr Moore noted: “For a patient who’s folate receptor alpha–high, use of mirvetuximab is the first line of therapy in the setting of platinum resistance...likely the optimal place to use this just because with most things that we see that are effective, the earlier you use them, the higher the response rate and the longer the duration of response.”
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