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Researchers identified tumor-infiltrating CD4+ T cells specific for a mutated antigen expressed by a tumor from a patient with metastatic cholangiocarcinoma. Infusion of this patient with an expanded-population, mutation-specific T cell resulted in tumor regression and stabilization of disease.

Final rule reduces burdens to critical access hospitals, rural clinics; loosens physician supervision requirements.

The American Cancer Society Cancer Action Network (ACS CAN) initiated an advertising campaign earlier this week to emphasize the importance of federal dollars in the fight against the deadly disease.

Researchers in Canada have developed a model to simulate the cost of active surveillance versus immediate treatment among low-risk prostate cancer patients.

Researchers have identified that other than clogging the arteries, LDL can also promote metastatic cancer cells, which break away from the parent tumor, to reattach at distant site.

Cancer treatments are evolving to work more effectively, but consequently, their costs are rising. In 2013, cancer medicine spending reached $91 billion globally-up from $71 billion in 2008.

Enrollees in some of the health law's most popular plans will face high cost-sharing requirements that the pharmaceutical industry says could keep patients from getting the drugs they need.

Families of Arizona children who were forced to switch from the Children's Health Insurance Program (CHIP) to private plans sold in the federal marketplace are likely paying more and getting fewer benefits, according to a study by Georgetown University researchers released Thursday.

The molecular diagnostic testing company Myriad Genetics announced that it had signed a 3-year contract with UnitedHealthcare to make their myRisk cancer susceptibility test accessible to patients.

Merck announced that the FDA has granted a priority review for it's anti-PD-1 antibody, MK-3475, under the accelerated approval program, for the treatment of metastatic melanoma.

DermoScan, created by an engineering faculty at the University of Houston, can help screen for melanoma. It has already been used to diagnose a dermal bacterial disease in Africa, in a NIH-sponsored study.

Only 50 physicians and 4 hospitals that enrolled in the federal electronic health record (EHR) incentive payment program have reported achieving Stage 2 meaningful use of EHRs. Officials from the Centers for Medicare & Medicaid Services (CMS) said that due to these low numbers, many participating practitioners who did not achieve Stage 2 risk having their Medicare reimbursement payments lowered at the end of 2014.

Since the Obama administration launched its accountable care initiative as part of healthcare reform in 2012, the CMS has announced which hospital and physician networks in one of the programs have met cost targets and received shared savings. But so far, it has published little data on quality of care delivered by these networks, which were designed to deliver better care as well as lower costs for Medicare patients.

The Obama administration says the number of Medicare patients returning to hospitals within 30 days fell further in 2013, amounting to 150,000 fewer readmissions since January 2012.

The former Congressman discussed his goal of finding common ground on what constitutes mental health while at the 167th Annual Meeting of the American Psychiatric Association.

A new biomarker for esophageal cancer shows promise in improving screening for this deadly disease and its precursor, Barrett's esophagus.

The Centers for Medicare & Medicaid Services (CMS) reported that between 2002 and 2010, elderly healthcare spending grew at the slowest rate among all age groups, which, according to CMS, can be attributed to the recession.

Hospitalists to field changes in patient care delivery, health policies propelled by Obamacare for decades.

Bioengineers at Harvard have devised a chip with bone marrow to test chemotherapy and radiation-associated toxicity, bypassing the need to use animal models.

Cryotherapy, already being used for benign breast tumors and several other cancers, might prove effective in women with breast cancer tumors 1 cm or smaller in size.

Medicaid managed-care plans are demanding relief from state officials to meet mounting outlays for Gilead Sciences' wonder drug, while insurer WellPoint called Sovaldi its biggest watch item.

Vintafolide, jointly being developed by Merck and Endocyte, failed to present efficacy on PFS in Phase 3 trials, resulting in early termination.

OncologyCloud, a platform developed by Flatiron Health, is already in partnership with more than 25 cancer centers to help address some of the bottlenecks in cancer care.

Experts from the University of Pittsburgh Medical Center (UPMC) found that big data tools can play an important role in personalizing healthcare delivery methods. Transforming care delivery models is an essential component of health reform because tailored, value-based care will lower costs and improve quality of care.

Despite the considerable resources designated to PCORI, its future remains tenuous.

States did little to improve healthcare access, quality, costs and outcomes in the past five years, according to a Commonwealth Fund report. Researchers examined 42 health indicators between 2007 and 2012, and found that in many states, access and affordability of healthcare actually declined among adults younger than 65. Healthcare spending rose $491 billion, reaching $2.8 trillion nationally.

Non-small cell lung cancer (NSCLC) patients who experienced disease recurrence half a decade after surgery received a significantly higher dose of opioids postoperatively, researchers said here.

The CMS intends increase Medicare payments to hospices and also make several tweaks to policy definitions and procedures to ensure more accurate reimbursement.

Patients with locally advanced squamous cell carcinoma of the head and neck treated with hyperfractionated radiation therapy (HFX) experienced improved local-regional control and, with patients censored at five years, improved overall survival with no increase in late toxicity.