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Today the FDA approved the first biosimilar product in the United States. Zarxio (filgrastim-sndz), from Sandoz, Inc, is biosimilar to Amgen Inc's Neupogen (filgrastim), which was first licensed in 1991.

In patients with depression, antidepressants may be more important than statins, according to a study conducted at the Intermountain Medical Center Heart Institute in Salt Lake City, which will be presented at the American College of Cardiology's 64th Annual Scientific Session in San Diego.

A unique coaching project included not only traditional elements like nutrition and exercise but also stress management and sleep.

CMS has proposed several possible changes to the Medicare Shared Savings Program in an effort to attract new participants and to encourage current participants to continue with the program beyond their initial 3-year commitment.

in some of the largest states that did not expand Medicaid, many safety-net hospitals fared pretty well last year-even better than in 2013 in many cases.

Drug-resistant strains of disease (aka "superbugs") have spread in recent years through hospitals, nursing homes, even locker rooms.

Twitter can be used as a real-time measurement of public sentiment for the Affordable Care Act (ACA) and the positivity and negativity of tweets could be used to determine state-level marketplace enrollment, according to researchers.

New proposals from Congress would decrease Medicare payments to hospital outpatient departments, which traditionally serve patients who are more likely to be minority, poorer, and have more severe chronic conditions compared with patients treated in physician offices.

A guideline has been issued that outlines the use of 3-D computed tomography-based radiation therapy planning and volumetric image guidance to more effectively treat pediatric Hodgkin lymphoma and to reduce the radiation dose to normal tissue, thus decreasing the risk of late side effects.

Harold Varmus, MD, who has led the National Cancer Institute at the National Institutes of Health for nearly 5 years, announced today that he will step down from his post, effective March 31, 2015.

A recent audit report out of New York serves as an example of state Medicaid programs that may not be maximizing their collection of revenue from drug rebates for Medicaid managed care enrollees.

AbbVie will spend about $21 billion to buy leukemia drugmaker Pharmacyclics in its first major deal attempt since walking away from a $55 billion takeover of Shire last fall.

The study, which will presented next week at the meeting of the American College of Cardiology, defined how much avoiding diabetes, obesity, and hypertension before age 45 matters if one is later diagnosed with heart failure.

In their latest attack on the Affordable Care Act, House Republicans question why the Obama administration transferred money last year from the National Institutes of Health and the CDC to pay for the operation of the federal health insurance marketplace.

While some progress has been made to disseminate comparative effectiveness research as mandated by the Affordable Care Act, the Agency of Healthcare Research and Quality has not taken actions to fully address requirements, according to a report from the Government Accountability Office.

After more than 3 decades helping individuals with mental health issues, Wayne Katon, MD, director of the division of health services and epidemiology, and vice chair of the department of psychiatry and behavioral sciences, University of Washington Medical School, passed away on March 1 from lymphoma at the age of 64 years.

The FDA announced today that it has approved Opdivo (nivolumab) for use in NSCLC patients who have progressed on or after platinum-based chemotherapy.

The Supreme Court's liberal wing grilled the petitioner's attorney on whether today's argument squared with what he said in the 2012 challenge to the Affordable Care Act. Justice Kennedy asked how states could be forced to set up exchanges or see their residents lose tax credits.

Keep up-to-date with the latest news from the oral arguments in the King v. Burwell case.

Brain tumor patients who are uninsured or use Medicaid stay hospitalized longer and develop more medical complications than those with private insurance, University of Florida Health researchers have found.

The study found that funding cuts could disrupt training of 550 medical residents and exacerbate primary care shortage.

While the pharmaceutical industry has always justified the billions spent on developing a candidate drug molecule, the process has definitely seen some important changes. This article evaluates whether these revolutionary changes have influenced drug development for the better.

On March 4, The American Journal of Managed Care will be live-reporting the news from the Supreme Court oral arguments in the case of King v. Burwell. In the meantime, here is a recap of the news leading up to the lawsuit's day in court.

The technique, L-COSY, monitors biochemical changes in tissue and could improve the management of women at risk of breast cancer, such as those carrying mutations in BRCA1 and BRCA2.

While the majority of primary care physicians are aware of and use state prescription drug monitoring programs to reduce drug abuse and diversion, many do not access these programs routinely, according to researchers from the Johns Hopkins Bloomberg School of Public Health.

The study in Health Affairs published by Samir Soneji, PhD, an assistant professor at Dartmouth's Geisel School of Medicine and The Dartmouth Institute for Health Policy & Clinical Practice, found that despite a sharp rise in healthcare spending,caner mortality rates are very high in the US compared to Western Europe.

Under the Affordable Care Act, CMS is charged with evaluating how well accepted quality measures are working to help meet a National Quality Strategy.

Awareness of chronic kidney disease remains low in the United States, yet the prevalence of the disease will rise over the next 15 years, according to a model developed by RTI.

Federal investigators say they have found evidence of widespread overuse of psychiatric drugs by older Americans with Alzheimer's disease, and are recommending that Medicare officials take immediate action to reduce unnecessary prescriptions.

The use of adjuvant systemic therapy for localized gastrointestinal stromal tumors has significantly increased over time, a new study published in the American Journal of Clinical Oncology, has found, and patients treated with the therapy have better survival than those treated with surgery alone, researchers say.