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A combination of KN026, a novel bispecific antibody, and docetaxel elicited responses with an acceptable toxicity profile when administered as neoadjuvant treatment in patients with HER2-positive (HER2+) early or locally advanced breast cancer.

At this year’s Community Oncology Alliance Payer Exchange Summit on Oncology Payment Reform, leaders from across all facets of the cancer care space engaged in thought-provoking panel discussions and debates. They have a common aim: to optimize cancer care delivery and ensure patients have a positive experience throughout their cancer care journey.

Clostridioides difficile risk is significantly higher in Korean patients with inflammatory bowel disease (IBD), which is comparable to the trend observed in Western patients with IBD.

“Unfortunately, limited access to these therapies worldwide appears to be a major challenge,” the researchers wrote.

Our most-viewed cardiovascular content includes research showing that a heart-healthy diet lowers cardiovascular disease risk by 30%; an interview with Stephen Nicholls, PhD, MBBS, on the SURPASS-CVOT trial; and more.

An observational registry study revealed that inflammatory disease activity is not the only factor influencing the achievement of treatment targets for patients with rheumatoid arthritis (RA).

More than 15.3 million Americans enrolled in health insurance under the Affordable Care Act for 2024, which is a 33% increase from last year; emergency contraception sales in the United States may spike by around 10% in the new year; top Biden administration officials met with prominent civil rights and public health leaders on Tuesday amid the decision to delay the menthol cigarette ban.

An in-depth look into what the drug is being used for and what has contributed to the shortage.

Key highlights from SLEEP 2023: long COVID-19's impact on sleep, racial disparities in sleep health, idiopathic hypersomnia prevalence, disrupted nighttime sleep's link to narcolepsy in children, and the ease of transitioning to lower-sodium oxybate in narcolepsy treatment while maintaining effectiveness.

Patients with immune-mediated thrombotic thrombocytopenic purpura (TTP) were found to have white matter damage in the frontal lobe and cingulate cortex that could affect short-term memory and depressive scores.

Researchers assessed care and costs incurred by people with asthma, who account for a large share of hospital admissions.

Patients with colorectal cancer (CRC) had reduced readmissions when treatment focused on preventing prolonged ileus, increasing the use of minimally invasive surgery, and preventing anastomotic leaks.

A one-size-fits-all approach to alternative payment models (APMs) often isn’t very fair to community practices, said Miriam Atkins, MD, FACP, president of the Community Oncology Alliance.

This year’s top content in the Duchenne muscular dystrophy (DMD) space focused on a novel gene therapy approval, the high cost of care for this genetic disorder, and steps forward in other treatments.

A single-center, observational study conducted in the Czech Republic investigated the determining factors in delayed diagnoses in multiple sclerosis (MS) and how these delays impact patient outcomes.

This year’s most-read respiratory articles explored a variety of topics, including the effects of marijuana and vaping on the lungs.

Understanding these relationships is crucial for developing effective clinical management strategies for patients with AD, according to a recent literature review.

A study investigating potential subtypes of idiopathic hypersomnia (IH) found that patients with IH who experience unrefreshing naps have less fragmented sleep compared with those who take refreshing naps, suggesting unrefreshing naps could serve as a supportive IH clinical feature.

The top-read topics in HIV for 2023 included dried blood tests for HIV, people with HIV facing stigmas, and vitamin D supplementation in women with HIV.

The FDA approved the first test to assess opioid addiction risk; Americans are using more cold and allergy medicines to mask any related symptoms to return to work and social gatherings, but may be overtreating themselves in the process; Rite Aid will be banned from using artificial intelligence–powered facial recognition technology for 5 years under a proposed Federal Trade Commission settlement.

Areas where fireworks were legal had slightly higher odds of firework-related ocular trauma in their residents.

Patients with non–small cell lung cancer (NSCLC) who tested positive for driver gene alteration had longer overall survival when given targeted therapy.

This year’s top 5 most-listened to podcasts included topics on digital health solutions, cardiology, value-based care initiatives, and oncology.

The most-read content from the 2023 American Society of Hematology Annual Meeting and Exposition included the latest in treating hematologic malignancies, the hope brought by novel therapy strategies, and the potential for artificial intelligence to improve diagnostic accuracy.

Baricitinib is more commonly prescribed by dermatologists for patients with alopecia in the United States and is projected to maintain a substantial market lead over ritlecitinib.

Increased pulmonary arterial hypertension (PAH) awareness and earlier screening in routine clinical practice could provide an opportunity for earlier treatment, resulting in reduced economic burden for payers, employers, and society at large.

A new survey from the National Alliance of Healthcare Purchaser Coalitions found that employers are planning to place a larger focus on obesity management, women’s health, and health equity in 2024 and beyond.

Bio-Thera Solutions’ Avzivi (bevacizumab-tnjn) has become the fifth biosimilar referencing Avastin (bevacizumab) to be approved in the United States.

From the 2023 Academy of Managed Care Pharmacy (AMCP) Nexus meeting, held in October, expert interviews and insightful updates on the Inflation Reduction Act, gene therapy affordability and access, and the 340B Drug Pricing Program comprise the conference highlights.

Justin Bekelman, MD, director of the Penn Center for Cancer Care Innovation, sat with our hosts Emeline Aviki, MD, MBA, and Stephen Schleicher, MD, MBA, for our final episode of 2023 to discuss the importance of collaboration between academic medicine and community oncology and testing innovative cancer care delivery in these settings.