Phase 3 CARTITUDE-4 Results Show Superiority of Cilta-Cel in MM
June 10th 2023The first phase 3 results from the CARTITUDE-4 trial of ciltacabtagene autoleucel (cilta-cel) vs standard of care in lenalidomide-refractory multiple myeloma (MM) demonstrated the former’s convincing superiority in several key outcomes.
Read More
Dr Jennifer Brown Speaks on Use of BTK, BCL-2 Inhibitors in CLL Treatment
June 10th 2023Jennifer Brown, MD, PhD, Dana-Farber Cancer Institute, shared her thoughts on the current research regarding Bruton tyrosine kinase (BTK) and B-cell lymphoma 2 (BCL-2) inhibitors in chronic lymphocytic leukemia (CLL) and what providers should keep in mind before prescribing them.
Watch
Dr Hans Lee Discusses Infection Risks for Bispecific Therapies for Patients With MM
June 10th 2023MD Anderson Cancer Center's Hans Lee, MD, shared considerations for possible infection risk associated with bispecific therapies used to treat relapsed/refractory multiple myeloma (MM) at the European Hematology Association 2023 Congress
Watch
Patients With BRCA-Mutated mCRPC Show Worse Outcomes vs Non-BRCA HRR mCRPC
June 10th 2023An analysis of patients with metastatic castration-resistant prostate cancer (mCRPC) and homologous recombination repair (HRR) deficiency mutations showed that patients with BRCA mutations had poor outcomes compared with those without BRCA mutations and those with non-BRCA HRR mutations.
Read More
Experts Spar Over Role of Real-World Data as Replacement for Clinical Trials in Hematology
June 9th 2023A friendly debate held at the European Hematology Association 2023 Congress focused on the potential for real-world data to improve the generalizability of clinical trial results but also acknowledged the limitations and current challenges with these data.
Read More
Dr Samyukta Mullangi: To Affect Prescribing Behavior, Payer Incentive Alignment Is Critical
June 9th 2023If payers can agree on consensus criteria to improve care quality or costs, that will help physicians remember and try to be compliant, said Samyukta Mullangi, MD, MBA, incoming medical director at Thyme Care.
Watch
Burgeoning Immunotherapy Options in Oncology Move Beyond CAR T and the Usual Disease States
June 9th 2023The use of immune therapies for hematological malignancies is expanding beyond chimeric antigen receptor (CAR) T-cell therapies in the traditional lymphoid disease states, but the impact on patient quality of life must remain top of mind, according to speakers at the European Hematology Association 2023 Congress.
Read More
A Q&A With the NIEHS’ Dr Symielle Gaston: Understanding Racial/Ethnic Variations in Sleep Health
June 8th 2023In this interview with The American Journal of Managed Care®, Symielle A. Gaston, PhD, MPH, of the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health, explores the relationship between sleep health and outcomes disparities among patients of various races and ethnicities.
Read More
Dr Sheila Garland: CBT for Insomnia Improves Functioning in Patients With Cancer
June 7th 2023Targeting insomnia with cognitive behavior therapy is almost like a frontline therapy, because by doing so, you’re able to improve a whole host of other symptoms that would coexist with insomnia, explained Sheila Garland, PhD, MSc, Memorial University in Newfoundland, Canada.
Watch
Dr Andrew McHill Discusses Damaging Sleep-Related Blood Pressure Changes
June 7th 2023Research is finding that there is an intricate connection between sleep and inflammation, such that lack of sleep can increase inflammation, noted Andrew McHill, PhD, an assistant professor at Oregon Health and Science University.
Watch
Dr Robert Sidbury: Best Practices for Managing Atopic Dermatitis in Infants
June 6th 2023Robert Sidbury, MD, MPH, professor of pediatrics at Seattle Children's Hospital, discusses best practices that physicians and parents of infants with atopic dermatitis (AD) can do to help manage flare- ups, as well as barriers to care, which he presented at the Revolutionizing Atopic Dermatitis conference.
Read More
Dr Dayna Johnson: Mindfulness Can Help Facilitate Better Sleep and Health Outcomes
June 6th 2023Dayna Johnson, PhD, MPH, MSW, MS, the Rollins School of Public Health at Emory University, discusses principal findings from the analysis of a 35-day sleep intervention study that utilized a mobile mindfulness app to manage stress and anxiety combined with healthy sleep practices.
Watch
Dr Ariel Williamson: Family Environment Is Crucial When Tailoring Sleep Interventions
June 6th 2023It’s important to consider the social context, the social ecology, and the family environment when investigating behavioral sleep problems among children and adults, noted Arielle Williamson, PhD, DBSM, Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine.
Watch
More Work Is Needed to Bring Clinical Trials to Underserved Patients, ASCO Panel Says
June 6th 2023While efforts are underway to improve access to cutting-edge oncology clinical trials for underserved patients, more work is needed to get the job done, said a panel of experts at the 2023 American Society of Clinical Oncology Annual Meeting.
Read More
ZUMA-7 Findings Show Earlier Is Better for Axi-Cel Use in R/R LBCL, Says Dr Jason Westin
June 5th 2023Jason Westin, MD, MS, FACP, director of the Lymphoma Clinical Research Program at the University of Texas MD Anderson Cancer Center, gave insight the ZUMA-7 trial of axicabtagene ciloleucel (axi-cel) in relapsed or refractory large B-cell lymphoma (R/R LBCL) and the study's implications in the broader LBCL landscape.
Watch
Dr Judy Wang on the Potential of CLN-619 for the Treatment of Solid Tumors
June 5th 2023Judy Wang, MD, medical oncologist and clinical trials investigator at Sarah Cannon Research Institute at Florida Cancer Specialists & Research Institute, discussed the mechanism of action and rationale for studying CLN-619, an anti-MICA/B antibody, with and without pembrolizumab in patients with solid tumors.
Watch
Dr Bhagirathbhai Dholaria Discusses TRiMM-2 Trial Findings
June 4th 2023Bhagirathbhai R. Dholaria, MD, assistant professor of medicine in the Department of Hematology-Oncology at Vanderbilt University Medical Center, discussed findings from the phase 2 TRiMM-2 trial of talquetamab plus daratumumab in multiple myeloma.
Watch
Social Determinants of Health Impact Germline Testing Rates Among Patients With TNBC
June 4th 2023Barb Kunz, MS, LCGC, senior genetic counselor at the US Oncology Network, shared insight on a study of social determinants of health in the context of germline genetic testing for triple-negative breast cancer (TNBC) in the community oncology setting.
Watch