NOW AVAILABLE: A Special Report on Diabetes Innovation 2012
December 31st 2012To act as a catalyst for ideas, partnerships, and collaboration among all stakeholders to provoke thought, innovation, and action to address the cost, productivity, and quality-of-life impact of diabetes, obesity, and related conditions and comorbidities on our society, Joslin Diabetes Center convened Diabetes Innovation for the first time in 2012. Highlights from Diabetes Innovation, which took place on September 23-25 2012, in Arlington, Virginia, are available in a special report published by The American Journal of Managed Care.
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At the 54th Annual Meeting of the American Society of Hematology, John Radford, MD, reported the results of the United Kingdom RAPID trial, in which PET-directed therapy provided an opportunity to avoid involved field radiotherapy, the current standard of care following abbreviated chemotherapy in early stage Hodgkin's lymphoma.
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Vorinostat Added to Standard Chemotherapy Reduced the Incidence of Acute GVHD
December 10th 2012Vorinostat added to standard chemotherapy before, during, and after hematopoietic stem cell transplantation reduced the cumulative incidence of graft-versus-host disease in a phase I/II trial reported at the 54th Annual Meeting of the American Society of Hematology.
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Adrian Wiestner, MD, PhD, Investigator, Laboratory of Lymphoid Malignancies, National Heart Lung and Blood Institute, discusses the patient outcomes that clinical trials have demonstrated regarding the use of targeted kinase inhibitors for the management of chronic lymphocytic leukemia (CLL).
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Selective Inhibitor of FLT3 Allows High-Risk AML Patients to Bridge to Stem Cell Transplant
December 10th 2012A unique targeted therapy, quizartinib, was able to clear leukemia cells from the bone marrow in more than 33% of patients with an aggressive form of acute myeloid leukemia marked by a mutation in the FLT3 gene.
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Elisabeth M. Paietta, PhD, Professor, Department of Medicine (Oncology), Albert Einstein College of Medicine, defines minimum residual disease (MRD) and discusses its clinical significance. She then describes the methodological and therapeutic challenges that face clinical MRD implementation.
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Encouraging Phase II Data for All-Oral First-Line Regimen in Newly Diagnosed Multiple Myeloma
December 9th 2012An investigational, weekly, oral proteosome inhibitor called MLN9708 achieved excellent response rates when combined with lenalidomide and dexamethasone as up-front treatment of newly diagnosed patients with multiple myeloma, according to results of a phase II trial presented at the 54th Annual Meeting of the American Society of Hematology.
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Thomas P. Loughran, Jr, MD, Professor of Medicine, Penn State University, Director, Penn State Hershey Cancer Institute, describes the clinical sequelae of large granular lymphocyte (LGL) leukemia, particularly noting neutropenia and anemia, and discusses the pharmacotherapeutic approach.
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Preliminary Evidence Suggests Ibrutinib Is a Home-Run for CLL
December 9th 2012Ibrutinib, an investigational Bruton's tyrosine kinase inhibitor, achieved excellent results in clinical trials of patients with chronic lymphocytic leukemia (CLL) presented at the 54th Annual Meeting of the American Society of Hematology.
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Richard T. Hoppe, MD, Discusses the Current Role and Utility of Radiation Therapy
December 9th 2012Richard T. Hoppe, MD, Professor of Radiation Oncology - Radiation Therapy, Stanford School of Medicine, discussed the current role and utility of radiation therapy in patients with early stage Hodgkins Lymphoma when compared to conventional chemotherapy.
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Extending Anticoagulation With Apixaban Reduces Recurrent VTE
December 9th 2012Extended anticoagulation with fixed doses of the oral Factor Xa inhibitor apixaban significantly reduced the incidence of symptomatic recurrent venous thromboembolism (VTE) or death without increasing the risk of major bleeding in patients with VTE who had already completed up to 12 months of anticoagulation.
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Claire E. Dearden, MD, Consultant Hematologist, Head of CLL Clinic, Royal Marsden Hospital, London, UK, highlights the pharmacotherapeutic strategies for the management of B- and T-cell PLL, noting the clinical outcomes associated with the diseases, and briefly touches on the future of PLL therapy.
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Health Plans Must Reconcile Consumer Needs and Internal Change in an Evolving Marketplace
December 4th 2012An expanding retail marketplace means that there are more opportunities for health plans to develop innovative strategies to reach consumers that are entering the market space for the first time. It is essential for health plans to not only engage these consumers but also to assist them in making good healthcare decisions.
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Ashish Jha, MD, MPH, Talks About Healthcare Delivery System Transformation
December 4th 2012Ashish Jha, MD, MPH, associate professor of Health Policy and Management, Department of Health Policy and Management, Harvard School of Public Health, says that there are many challenges facing the quality of data used to transform healthcare delivery systems.
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Big Data Pitfalls Still Plague Healthcare Industry
December 4th 2012Incomprehensible amounts of data are collected by all sectors of the healthcare industry on a daily basis. It is important for organizations to not only understand how to handle and collect this data, but also to translate it into actionable information that can help transform healthcare delivery. Unfortunately, many pitfalls still exist, and there is a need for better processes to collect clinically relevant and more complete data.
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Cindy Bjorkquist Addresses Engaging Consumers in the Healthcare Marketplace
December 3rd 2012Cindy Bjorkquist, Director of Wellness, Care Management and Health Promotion Programs Development, Blue Cross Blue Shield of Michigan, discusses Blue Cross Blue Shield of Michigan's Total Health Improvement Strategy.
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Health Plans Must Diversify Tools for Patient Engagement
December 3rd 2012Day 1 of the America's Health Insurance Plans Fall Forum 2012 featured a pre-conference workshop on patient engagement strategies to promote wellness in a consumer-driven marketplace. Presenter and moderator Jen Cressman, Vice President, Strategic Accounts, Krames StayWell, centered her discussion on the design of effective communication strategies and how to attract and engage consumers while also fostering loyalty.
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Shared Decision Making Is an Effective Model for Patient-Centric Care
December 3rd 2012Healthcare is in the midst of a shift toward more patient-centric and accountable care; as a result, time- and resource-constrained providers are embracing new and innovative models for delivering and organizing care.
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NOW AVAILABLE: AMCP Fall 2012 Conference Coverage
November 30th 2012Highlights from the Academy of Managed Care Pharmacy's 2012 Educational Conference, which took place on October 3-5, 2012, in Cincinnati, Ohio, are available in a newsletter published by The American Journal of Managed Care. Topics discussed include the ways in which heterogeneity shapes therapeutic decisions, patient outcomes, and coverage policies; assessment of the evidence for new medications; and phone-based medication therapy management services.
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Payer Management of Oncology: An In-Depth Look
November 19th 2012On Friday, November 16, The American Journal of Managed Care hosted its first annual live meeting, "Translating Evidence-Based Research into Value-Based Decisions in Oncology." The conference, which brought together stakeholders from all sides of the managed care industry, provided an arena for healthcare professionals to discuss new, innovative payment models being utilized by both payers and providers.
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Peter Bach, MD, MAPP, Talks About Improving Quality in Cancer Care
November 19th 2012Peter B. Bach, MD, MAPP, Director, Center for Health Policy and Outcomes, Attending Physician, Memorial Sloan-Kettering Cancer Center, states that any organizational change that shifts payment and risk to providers will improve quality.
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