Migraine

Results from a questionnaire-based study indicated an association between a history of abuse and increased sensory hypersensitivity symptoms among migraineurs.

A review published in Neuropsychiatric Disease and Treatment highlights the lack of research on migraine prevalence and symptoms among postmenopausal women.

Results of a retrospective cohort study show that utilization of erenumab was associated with a decreased use of acute and preventive prescription migraine medications. Although adherence to erenumab was higher than other traditional oral prophylactic migraine therapies, adherence rates can be improved.

Researchers used deidentified real-world data to assess characteristics of patients who have received erenumab since its approval.

A cross-sectional study explores the relationship between magnesium, calcium dietary intake, and migraine among men and women.

Randomized clinical trial results published in Cephalalgia show that trans-nasal high-flow dry gas therapy may play a role in reducing migraine-associated pain.

Compared with healthy controls, patients with episodic migraine and patients with chronic migraine exhibited differing structural brain network characteristics, potentially indicating maladaptive reorganizations of headache-related brain circuits which could lead to migraine attacks or secondary alterations to pain.

Results of a scoping review of 19 studies indicate estrogen likely plays a key role in migraine pathogenesis but affects patients in different ways depending on past medical history, age, and use of hormonal therapy.

In a review published in Eye and Brain, researchers outlined the link between dry eye and migraine, their possible shared pathophysiology, and therapies targeting similar pathophysiological mechanisms.

More treatment methods focused on reducing functionality loss and adopting multidisciplinary and prospective approaches via psychiatric screening should be developed for adolescents with chronic migraine (CM), researchers writing in BMC Neurology concluded.

Posttraumatic headache (PTH) with a migraine phenotype is associated with persistent symptoms following concussion, compared with nonmigraine PTH or no PTH, according to study results published in JAMA Network Open.

Findings suggest that including slowly repeated evoked pain (SREP) in quantitative sensory testing protocols may enhance assessments of altered pain modulation in different pain conditions.

Based on the findings, researchers suggest it may be beneficial to advise patients with chronic migraine and medication overuse headache (MOH) to reduce cannabis use to effectively treat MOH.

Although the exact underlying pathogenesis of migraine remains unknown, lifestyle modifications with regard to stress, sleep, exercise, and dietary considerations have been reported as beneficial for moderate clinical features.

More than two-thirds of individuals suffering from migraine do not get enough exercise, according to preliminary study findings. However, migraineurs who complete a minimum 2.5 hours of moderate to vigorous exercise a week exhibited reduced rates of migraine triggers including stress, depression, and sleep problems.

Patent foramen ovale (PFO) may be associated with migraine, especially migraine with aura (MA), when the PFO is permanent right-left shunt (RLS), large RLS, and large-size PFO, a recent study found.

An anxiety screening tool should be included during initial assessments of migraineurs by medical practitioners, according to the authors of a systematic review published in Frontiers in Neurology.

In a review published in Frontiers in Psychiatry, researchers outlined potential mechanisms accounting for comorbid bipolar disorder and migraine and examined therapeutic targets for treatment to improve prognosis in these patients.

Migraine is a potential risk factor for asthma and asthma is a potential risk indicator for migraine, authors of a systematic review and meta-analysis concluded.

Survey results indicate a significant association exists between migraine and arthritis among women, adults aged 45 years or less, and those over age 65.

Among patients with episodic migraine in whom 2 to 4 preventives were not useful, erenumab was efficacious in improving functional outcomes after 12 weeks of treatment.

Treatment with erenumab led to improvements in pain, medication use, and quality of life in onabotulinumtoxinA-resistant patients with chronic migraine, according to study results published in The Journal of Headache and Pain.

Key opinion leaders discuss the various adverse events of emerging CGRP monoclonal antibody treatments and compare efficacy data.

A discussion on emerging CGRP monoclonal antibodies for the prevention of migraine onset.

A retrospective analysis of preventive care and how advancements have allowed for more effective management of migraine.

Experts in the management of migraine consider the factors that contribute to transitioning a patient from acute to preventive care.

Key opinion leaders discuss the process of determining and measuring individualized treatment goals to ensure patients with migraine receive the most effective management.

A discussion on how advancements in migraine understanding have improved diagnostics and treatment.

Migraine specialists consider the drivers of health care utilization for uncontrolled migraine and discuss where individuals go to seek help for management.

Key opinion leaders briefly discuss unmet needs in the acute migraine space and how to determine when to switch from an acute agent.