The AJMC® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.
December 23rd 2024
Some of the top heart failure research looked at statins and semaglutide for heart failure with preserved ejection fraction, diabetes-related heart failure risks, and the protective cardiovascular effects of COVID-19 vaccination.
November 18th 2024
Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment
1.5 Credits / Cardiology, Neurology, Rare Diseases
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The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation
1 Credit / Cardiology, Neurology
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Evidence-Based Guidelines Point to Leap in Care for Hypertrophic Cardiomyopathy
1.0 Credit / Cardiology
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Cost-Benefit Analysis of Sacubitril/Valsartan in a Medicaid Population
The cost avoidance of heart failure–related hospitalizations and emergency department visits may outweigh the additional drug cost in Medicaid members adherent to sacubitril/valsartan.
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Potential Link Found Between Heart Failure Prognosis, Changes in RVFAC
July 8th 2022Few data exist on how right ventricular fractional area change (RVFAC) may contribute to outcomes among patients hospitalized for heart failure, so that potential relationship was investigated in this new study from Japan.
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Exercise Capacity in HFpEF Not Impaired by Reduced Diastolic Filling Time
July 2nd 2022Using chronotropic response as a reference, study authors from Japan investigated the potential influence of exercise-induced heart rate on cardiac output reserve and exercise capacity among a cohort of patients with heart failure with preserved ejection fraction (HFpEF).
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Gout Flare Likely Increases Hospital LOS in Heart Failure
June 25th 2022Using the Nationwide Inpatient Database for trends studied between 1993 and 2011, investigators from Columbia University Irving Medical Center evaluated hospitalization outcomes among patients with heart failure and comorbid gout.
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Patients With HFrEF May Benefit From Alternate Method of Sac/Val Dose Titration
June 22nd 2022In this study, Italian investigators evaluated how sacubitril/valsartan (Sac/Val) dose titration among older patients with heart failure with reduced ejection fraction (HFrEF) might affect reverse cardiac remodeling and if the success of up-titration can be predicted.
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Sacubitril/Valsartan Safe, Effective Among CHF Patients on Maintenance Hemodialysis
June 18th 2022Outcomes in this new study, conducted among patients with chronic heart failure (CHF) on maintenance dialysis and receiving sacubitril/valsartan, were evaluated as they pertained to heart function and blood pressure.
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Caregiver Contributions in Heart Failure Require Further Study
June 16th 2022The primary outcomes of this secondary analysis of the MOTIVATE-HF study were improvement in caregiver self-efficacy while caring for patients living with heart failure and caregiver contributions to self-care for these patients following motivational interviewing.
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Sacubitril/Valsartan Reduces mPAP, Improves Functional Capacity in HFpEF-PH
June 3rd 2022Sacubitril/valsartan reduced mean pulmonary artery pressure (mPAP) and improved lung congestion, functional capacity, and quality of life in a subset of patients with heart failure with preserved ejection fraction and pulmonary hypertension (HFpEF-PH) using a remote monitoring platform.
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New Research Calls for a Reconsideration of Loop Diuretic Use, Fluid Restriction in HF
May 25th 2022Thirst outcomes were investigated among patients with stable heart failure (HF), due to the limited data available on this relationship and how it, along with fluid and sodium intake, influences clinical outcomes in this population.
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Study: Sacubitril/Valsartan Led to Fibrosis Improvements in HFrEF
May 20th 2022This study evaluated levels of 4 biomarkers associated with heart failure with reduced ejection fraction (HFrEF) before and after treatment with the angiotensin receptor neprilysin inhibitor sacubitril/valsartan.
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Superior Clinical Outcomes Seen in HFrEF With Early Initiation of Sacubitril/Valsartan
May 16th 2022Two periods of sacubitril/valsartan initiation were compared in a study population of patients with heart failure with reduced ejection fraction (HFrEF): less than 3 months or 3 or more months following first HFrEF diagnosis.
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Remote Monitoring Not Successful at Reducing Death, Readmission From HF
May 9th 2022In this study, investigators from Pennsylvania and New York evaluated outcomes among patients following their hospitalization for heart failure (HF) who did or did not participate in a remote monitoring program that included financial incentives for adherence.
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Cardiac Rehab Linked to Improved Mortality Among Patients With HFrEF
May 6th 2022In this study, outcomes were investigated among a cohort of patients with heart failure with reduced ejection fraction (HFrEF) who participated in a cardiac rehabilitation program post hospital discharge after they survived acute onset of HFrEF.
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Study Calls for Sex-Specific Tactics to Reduce Rising Heart Attacks in Young Adults
May 3rd 2022These investigators wanted to better understand the reasons for the increased risk for acute myocardial infarctions among young women, who have the largest increase in hospitalization for heart attacks.
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NT-proBNP Level May Influence HF Risk Among Blacks vs Whites, Men vs Women
April 27th 2022In this new subanalysis of data from the Atherosclerosis Risk in the Communities study, investigators assessed the risk of incident heart failure (HF) or death by race and sex, as influenced by N-terminal pro–B-type natriuretic peptide (NT-proBNP) concentration, prompted by growing interest in its use as a predictive biomarker for HF.
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USPSTF Updates Preventive Aspirin Use Recommendation in CVD, CRC
April 26th 2022There may be a small, but not overwhelming, benefit for certain individuals aged 40 to 59 years who have a slightly elevated risk of future cardiovascular disease (CVD) to start taking aspirin, according to an update released by the US Preventive Services Task Force (USPSTF).
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Long-term Cardiac-Related Mortality Likely Predicted by 30-Day Postsurgical Outcomes
April 18th 2022This study investigated long-term cardiac-related mortality as it relates to incidence of perioperative adverse cardiac events (excluding death) in the first 30 days after surgery among a short of patients who underwent non–cardiac-related surgery.
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Contributor: How Pediatric Mental Health May Influence the Risk of Heart Disease in Adulthood
April 13th 2022In this contributor piece, the connection between the complexities of mental health and heart disease in at-risk communities is explored, with the authors stressing the importance of risk factor evaluation and multidisciplinary patient education from both mental and physical health providers.
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Formulary Placement Led to Delays, Disruptions in Receiving Sacubitril/Valsartan for CHF
April 8th 2022More than a quarter of patients experience disruptions and delays in treatment for chronic heart failure (CHF) after the initial prescription for sacubitril/valsartan was abandoned/rejected.
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What We're Reading: ACA Coverage Expansion; New Heart Failure Guidelines; Poor Air Quality Worldwide
April 5th 2022The Biden administration plans to expand Affordable Care Act (ACA) coverage to more families; new guidelines jointly announced by cardiology organizations for the treatment and prevention of heart failure; World Health Organization estimates that 99% of people worldwide are exposed to poor air quality.
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Morbidity, Mortality Improve in HFrEF With Combo Treatment vs Monotherapy
April 2nd 2022This new analysis of data from the Swedish Heart Failure Registry involved an investigation into the relationship between therapy count and dosing on mortality and morbidity among patients with heart failure with reduced ejection fraction (HFrEF).
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Coffee’s Preventive Benefits for CVD, Heart Disease on Display in Study Pair
March 30th 2022Two studies presented at the annual meeting of the American College of Cardiology show the safety and effectiveness of regular coffee consumption in regard to cardiovascular disease and heart disease, as well as mortality.
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HIIT Shown to Improve Cardiometabolic Risk in Heart Failure
March 24th 2022This study enrolled 80 middle-aged patients with stage A heart failure and evaluated them for improvements in several cardiovascular and metabolic risk factors through high-intensity interval training (HIIT) for 1 year and omega-3 fatty acid supplementation.
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