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A Natural Experiment in Mass Media Modulated Pharmacokinetics After a Change in Tablet FormulationSporadic, unsubstantiated side effects were reported in the mass media after a formulation change of levothyroxine tablets induced patients to monitor thyroid-stimulating hormone levels and to unnecessarily stop taking medication.
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CHAPTER 5. Clinical Guideline for Pharmacological Management of Adults With Type 2 DiabetesFrom the Adult Diabetes and Clinical Research Sections, Joslin Diabetes Center, Harvard Medical School. Approved May 10, 2016; updated April 24, 2018. For the Figure and Tables, download the PDF at the end of the chapter.
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Contributor: Patient-Centered Approaches to Supporting Medication Adherence Among Persons With SchizophreniaThere are effective strategies that can be employed concurrently to promote adherence to medications for schizophrenia, including but not limited to pharmacological, technological, and psychosocial interventions.
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Estimated Effect of Asthma Case Management Using Propensity Score MethodsAn asthma case management program increased preventive care but did not significantly decrease markers of exacerbations.
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Assessing Outcomes in Child PsychiatryTwo standardized rating scales appeared to be valid and reliable for use at admission and possibly follow-up in a child psychiatry system of care.
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Improving Influenza Immunization in Pregnant Women and Healthcare WorkersInfluenza vaccination rates in pregnant women and healthcare workers were increased with standing orders, vaccine advocates, and educational activities on influenza immunization.
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Impact of a Scalable Care Transitions Program for Readmission AvoidanceThe 30-day readmission risk was reduced 25% by a collaborative program model employing discharge planning and telephonic follow-up for high-risk patients with CMS penalty diagnoses.
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Understanding and Improving Value Frameworks With Real-World Patient OutcomesNew value frameworks should incorporate real-world evidence that reflects patient treatment behavior, adherence to medication, and equity concerns arising from disparities in care.
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Cost-Effectiveness of 21-Gene Assay in Node-Positive, Early-Stage Breast CancerA decision-analytic model was used to estimate cost-effectiveness of adopting a 21-gene assay in treatment decisions for women with early-stage N (1-3)/ER HER2-negative breast cancer.
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Improving Quality of Care in Oncology Through Healthcare Payment ReformOverview of alternative payment models and how leading national organizations are involved with linking quality improvement initiatives and payment reform.
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A Step in the Digital Direction: From Paper Logs to Electronic Data CaptureResearch documentation is a critical aspect of running a clinical trial. Key patient information such as informed consent, adverse events (AEs), concomitant medications, and medical and surgical histories are collected and used to determine patient safety and efficacy as the trial proceeds. Ultimately, the sponsor may make decisions—ranging from modifying the dose of the investigational drug to closing the study due to AEs—based on the data collected.
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Previously Unrecognized Trends in Diabetes Consumption Clusters in MedicareMedicare beneficiaries with diabetes who are at the lowest levels of healthcare consumption often become some of the highest level consumers in subsequent years.
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Costs of Asthma Among US Working AdultsAmong a working population, patients with asthma experienced significantly higher direct medical costs and modestly higher work loss than patients without asthma.
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Is Integration in Large Medical Groups Associated With Quality?Integrated care systems allegedly provide better care. This study of 97 large medical groups nationally provides suggestive evidence that this may be true.
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Simply Delivered Meals: A Tale of CollaborationOffering a meal delivery service to patients in a community-based care transition program was associated with cost savings and a 38% lower 30-day hospital readmission rate.
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Using Financial Incentives to Improve the Care of Tuberculosis PatientsPatients enrolled in the tuberculosis pay-for-performance program received more comprehensive ambulatory care with slightly lower costs and a higher treatment success rate.
