Black Patients More Likely to Receive High-Cost Care at End of Life
December 21st 2017Multiple studies have demonstrated that black Americans tend to receive more intensive, higher-cost care at the end of life, and have higher rates of hospitalization and lower rates of hospice enrollment. A new study sought to determine whether racial variation exists among hospice enrollees in rates of hospitalization and hospice disenrollment, and whether that variation could be explained by systematic differences in hospice provider patterns.
Study: Age, Education, and Income All Associated With Time to Diagnosis With Early RA
December 20th 2017A new study, published in The Korean Journal of Internal Medicine, sought to identify the factors associated with time to diagnosis of early RA after the onset of symptoms, and found that older age, higher educational level, higher income, and small joint involvement were all positive factors for early diagnosis of RA.
Conceptual Paper Proposes Four Cost-Reducing Interventions for In Vitro Diagnostics
December 14th 2017US healthcare spending is on the rise, and is expected to comprise over 20% of the gross domestic product by 2025. Current expenditures are expected to double by 2060 if the pace of spending in the past decade continues. In this healthcare landscape, in vitro diagnostics (IVD) have increasingly become the subject of scrutiny, as IVDs are perceived as contributing to soaring costs.
Bone Marrow Environment in Patients With RA May Promote Inflammation
December 13th 2017Though rheumatoid arthritis (RA) often leads to destruction of joints, the bone marrow environment appears to be an important site for the pathological processes of RA. A new study investigating interleukin-17 (IL-17) in bone marrow explored the role that this cytokine plays in inflammation and the process of bone destruction.
UC San Diego Researchers Receive $600,000 Grant to Test PI3Ky Inhibitor
December 9th 2017A University of California San Diego School of Medicine and Moores Cancer Center research team studying new drugs that could break resistance to cancer immunotherapy has received a 3-year, $600,000 translational grant from the V Foundation for Cancer Research.
Systematic Review Finds Elevated Reporting for Thromboembolic Events With JAK Inhibitors
December 5th 2017A systematic review of the FDA’s Adverse Event Reporting System (FAERS) found elevated reporting for both tofacitinib (Xeljanz) and ruxolitinib (Jakafi) for thromboembolic adverse events (AEs), suggesting the possibility of a class-wide issue with Janus kinase (JAK) inhibitors.
African Americans Are More Likely to Have MM, but Are Underrepresented in Research
November 30th 2017While African Americans are 3 times more likely than Caucasians to be diagnosed with multiple myeloma (MM)—and twice as likely to die of the disease—they are underrepresented in MM disease research.
5 Things to Know About the Nocebo Effect and Biosimilars
November 24th 2017The “nocebo” effect, a phenomenon that occurs when a patient’s negative perception of a therapy causes a treatment to have a worse outcome than would otherwise be expected, has become a topic of increasing interest in the world of biosimilars as some patients begin to transition from familiar, high-cost biologics to new, lower-cost biosimilars.
National Health Interview Survey Provides Early Insight Into Rates of Uninsured Americans
November 23rd 2017The National Center for Health Statistics has issued its early estimates from the National Health Interview Survey, conducted between January and June 2017. The report presents selected estimates, based on data for 39,480 people in the first 6 months of the year, on health insurance coverage for the US population.
Study Compares Methotrexate-Only Versus Combination Therapy in Early RA
November 21st 2017A recent study evaluated the treat-to-target strategy by assessing whether patients with early rheumatoid arthritis (RA) who start methotrexate as monotherapy had similar or worse outcomes compared with patients who started with adalimumab plus methotrexate.
Study Supports Use of Intravenous Golimumab in Treating Psoriatic Arthritis
November 17th 2017Recently reported results of a phase 3 study found that patients with psoriatic arthritis (PsA) who received intravenous golimumab (Simponi) had significantly greater improvements in the signs and symptoms of PsA through week 24 than did patients who received placebo.
Report: US Medical Health Research Spending on the Rise, but for How Long?
November 15th 2017Medical health research spending in 2017 is likely to increase, primarily due to an additional $2 billion earmarked for the National Institutes of Health, but the long-term outlook for research and development is uncertain. The authors cite the current administration’s calls for large cuts to federal research funding across non–defense-related areas as a potential cause of reduced spending on health research.
Maximal Tolerated Dose of Hydroxyurea Supported in Children With Sickle Cell Anemia
November 14th 2017Recently reported results from Hydroxyurea Study of Long-Term Effects (HUSTLE) support the use of hydroxyurea in children, and indicate that a preferred dosing strategy should target an HbF endpoint of greater than 20%.
Federal Agencies Address the Dual Crises of Pain and Opioid Addiction
November 8th 2017In a Tuesday panel discussion at The American College of Rheumatology’s 2017 Annual Meeting in San Diego, California, representatives from HHS, the National Institutes of Health (NIH), and the CDC outlined ongoing federal initiatives to address the parallel problems of pain and opioid addiction.
ACR and NPF Unveil New Clinical Guideline for Treating Psoriatic Arthritis
November 8th 2017On Tuesday afternoon, the American College of Rheumatology (ACR) and the National Psoriasis Foundation (NPF) presented a draft of their new, jointly developed clinical guideline for treating psoriatic arthritis (PsA), at the ACR 2017 Annual Meeting.
Value-Based Contracting in the "Era of Unknowns"
November 8th 2017In a Tuesday session at the American College of Rheumatology’s 2017 Annual Meeting in San Diego, California, Greg Mertz, MBA, FACMPE, managing director for Physician Strategies Group, LLC, presented a talk title “Value Contracting: Opportunities of Fantasy?” in which he outlined the current landscape for performance-based contracting.
2017 Sees Progress in Approvals for Anti-Rheumatic Drugs
November 7th 2017Kamala Nola, PharmD, MS, professor at the Lipscomb University College of Pharmacy, provided an overview of the drugs that have been approved in the past year for the treatment of inflammatory conditions during a session at the 2017 American College of Rheumatology Annual Meeting,
Rheumatology Patients at Increased Risk for Cardiac Disease
November 7th 2017During a session at the 2017 American College of Rheumatology Annual Meeting in San Diego, California, a cardiologist joined rheumatologists to give a detailed look at the relationship between rheumatic conditions and cardiovascular disease.
Rheumatologists' Frustrations With PBMs Take Center Stage
November 6th 2017The title "Reshaping the Relationship Between Physicians and PBMs" suggested that the Sunday session at the 2017 American College of Rheumatology’s Annual Meeting in San Diego, California, would focus on reconciling the goals of providers and pharmacy benefit managers (PBMs), but physicians’ challenges in dealing with PBMs quickly became the primary focus of the panel discussion.
Republican Tax Plan Has Far-Reaching Implications For Healthcare Stakeholders
November 4th 2017The Tax Cuts and Jobs Act introduced this week by House Ways and Means Committee Chairman Kevin Brady, R-Texas, proposes to lower individual tax rates for low- and middle-income Americans, increase the standard deduction, and add a new family tax credit, but the proposed legislation also has far-reaching implications for healthcare.