Trabectedin and Lurbinectedin Effective in BRCA2-Associated Metastatic Breast Cancer
July 18th 2017An interim analysis of two phase 2 trials, reported in a poster session at the 2017 American Society of Clinical Oncology Annual Meeting, has found that trabectedin and lurinectedin demonstrated remarkable activity as single agents in BRCA2-associated metastatic breast cancer.
Alectinib May Be a New Standard of Care for Treatment-Naïve ALK-Positive NSCLC
July 18th 2017A late-breaking abstract at the 2017 American Society of Clinical Oncology Annual Meeting showed that alectinib demonstrates efficacy and favorable tolerability compared with crizotinib in the primary results of the global phase 3 ALEX study in patients with treatment-naïve advanced anaplastic lymphoma kinase (ALK)-positive non—small cell lung cancer (NSCLC).
Dacomitinib a New First-Line Option for Advanced EGFR Mutation—Positive NSCLC
July 18th 2017ARCHER 1050, the first phase 3 head-to-head study of epithelial growth factor receptor (EGFR) tyrosine kinase inhibition, has produced results that demonstrate statistically significant and clinically meaningful improvement with dacomitinib compared with gefitinib (Iressa) as first-line therapy for non—small cell lung cancer (NSCLC) with EGFR-activating mutations.
Analysis of COPD Hospitalization Trends Finds Gender Gap for Mortality
June 20th 2017With more women dying annually from chronic obstructive pulmonary disease (COPD) than men since 2000, researchers have examined trends in COPD hospitalization and in-hospital mortality, evaluating for differences by sex and race. They presented their research at the American Thoracic Society 2017 International Conference.