Biosimilar Battle Reaches SCOTUS
On April 26, the Supreme Court will hear arguments in Sandoz v Amgen, which could have implications for how quickly biosimilars get to market. Politico provided background on the 2 questions being considered regarding the 180-day notice of intent to market and the patent-sharing process between biosimilar makers and branded biologic manufacturers. Sandoz is arguing that biosimilar companies should be able to provide the 180-day notice before FDA approval and that the patent-sharing is optional.
New Prostate Cancer Screening Guidelines
The US Preventive Services Task Force (USPSTF) has provided an update to its 2012 recommendation on prostate cancer screenings. CNBC reported that the new recommendation is that men between the ages of 55 and 69 should make individualized decisions based on clinician-patient discussions. Previously, USPSTF recommended no routine screening regardless of age, which some experts considered a mistake and was at odds with recommendations from the American Urological Association and the American Cancer Society.
Accuracy of Fitness Trackers
A new study has found that fitness trackers are not very good at monitoring heart rate when users move while exercising. According to the Los Angeles Times, fitness trackers are good at counting steps and monitoring heart rate during exercise only if you don’t move. When participants exercised on a treadmill, fitness trackers were way off compared with an electrocardiograph, which is used to conduct stress tests in a doctor’s office. However, this doesn’t mean people should throw out their trackers—they are still useful for helping people increase their exercise level.
Current and Emerging Options for Uncommon EGFR- and Exon 20 Insertion–Mutated NSCLC
September 8th 2025Uncommon EGFR mutations in non–small cell lung cancer (NSCLC) remain challenging to treat, but new tyrosine kinase inhibitors, bispecific antibodies, and a proposed “PACCage insert” framework provide opportunities to advance precision therapy.
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Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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Evolving Roles of Antibody-Drug Conjugates in the Treatment of NSCLC
September 7th 2025Antibody-drug conjugates are rapidly reshaping the treatment landscape of non–small cell lung cancer (NSCLC), with advances in design, clinical efficacy, and regulatory approvals tempered by ongoing challenges in toxicity, resistance, and biomarker optimization.
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From Amivantamab to Next-Generation Therapies: The Evolving Bispecific Antibody Landscape in NSCLC
September 6th 2025Bispecific antibodies are emerging as a transformative class in advanced non–small cell lung cancer (NSCLC), with agents such as amivantamab and zenocutuzumab already demonstrating clinical benefit and a broad pipeline of investigational therapies showing promise in overcoming resistance.
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