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What We’re Reading: AstraZeneca Updates Efficacy Data; Senate Confirms First Openly Transgender Official; Migrant Children Contract COVID-19
AstraZeneca releases updated efficacy data for its COVID-19 vaccine following scrutiny; Rachel Levine, MD, is confirmed as the first openly transgender person to serve in a federal position; hundreds of migrant children remain in isolation after testing positive for COVID-19.
AstraZeneca Data Confirm Vaccine Is Effective
After the Data Safety Monitoring Board (DSMB) questioned data released by AstraZeneca on its experimental COVID-19 vaccine, the company announced that analyses of more data show the vaccine is 76% effective at preventing symptomatic COVID-19, the Associated Press reports. That number is slightly less than the previously reported 79% efficacy announced earlier in the week. The DSMB expressed concerns that the company may have released outdated information on the trial that would provide an incomplete overview of the efficacy data. Some experts claimed the newly released data were reassuring and will likely serve as a stepping stone for US regulators to authorize the vaccine.
Senate Confirms Dr Rachel Levine as HHS Assistant Health Secretary
Rachel Levine, MD, has been confirmed by the Senate to be HHS’ assistant health secretary, making her the first openly transgender person confirmed to a federal position, The New York Times reports. Upon her confirmation, Levine vowed to promote policies advancing the health of all Americans and fight for transgender youth. Transgender adolescents attempt suicide at a much higher rate than youths whose gender identity matches the sex listed on their birth certificates. Levine was confirmed in a 52-48 vote, with Republican senators Lisa Murkowski of Alaska and Susan Collins of Maine crossing party lines to endorse the candidate.
Migrant Children Contract COVID-19, Remain in Isolation
Hundreds of migrant children detained at the United States–Mexico border have tested positive for COVID-19, according to The Hill. HHS data show there have been nearly 3000 lab-confirmed COVID-19 tests recorded among unaccompanied children since March 2020, and 2587 of that total have since recovered and moved out of medical isolation. Currently, 319 children remain in isolation due to a positive COVID-19 test while over 11,500 unaccompanied youths are in HHS shelters. The agency also currently runs more than 200 facilities in 22 states.
Real-World Data Support Luspatercept vs ESAs for Anemia in Lower-Risk MDS
June 5th 2025Patients with myelodysplastic syndrome (MDS) who received luspatercept showed greater hemoglobin gains and transfusion independence compared with erythropoiesis-stimulating agents (ESAs) in a real-world analysis.
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Laundromats as a New Frontier in Community Health, Medicaid Outreach
May 29th 2025Lindsey Leininger, PhD, and Allister Chang, MPA, highlight the potential of laundromats as accessible, community-based settings to support Medicaid outreach, foster trust, and connect families with essential health and social services.
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Alzheimer Disease and Related Dementias Cause Surging Economic Burden for Minoritized Communities
June 5th 2025African American and Latino older adults with Alzheimer disease and related dementias and their families are likely to face disproportionately high burdens, primarily associated with unpaid caregiving, suggesting the need for policies that may reduce economic burdens for all US residents.
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Use of Voluntary Alignment in the Next Generation ACO Model
June 5th 2025Use of voluntary alignment attribution by Next Generation Accountable Care Organization (ACO) participants was limited. The authors highlight the reasons and describe organizational use cases via a mixed-methods approach.
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