Top 5 Most-Watched Videos of 2024

The top 5 most-viewed videos of 2024 highlight key advancements in health care, including promising therapies for neurological conditions, innovative approaches to heart disease screening, and the complexities of pediatric palliative care. The videos also explore the consequences of medication disruptions on chronic disease management and emphasize the importance of incorporating economic research into health policy to optimize decision-making and resource allocation.

Here are AJMC.com’s 5 most-viewed videos of 2024.

The top 5 most-viewed videos of 2024 highlight advancements in healthcare, including therapies for neurological conditions, heart disease screening, pediatric palliative care, medication disruptions in chronic disease management, and the role of economic research in health policy. | Image credit: fabrus - stock.adobe.com

5. Dr Ari Green on Promising Remyelination Therapies and Patient Outcomes in MS

At the ACTRIMS Forum 2024, Ari Green, MD, chief of the Division of Neuroimmunology and Glial Biology at the University of California, San Francisco, discussed promising remyelination therapies for multiple sclerosis (MS), including clemastine, which has shown potential in clinical trials. He highlighted the importance of individual patient factors, such as disease stage and genetic differences, in influencing treatment efficacy. Green emphasized that combining remyelination therapies with ongoing immunomodulatory treatments could be key to successful long-term management of MS.

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4. New Data Suggest Screening Heart Disease by Identifying Plaque, Not Just Risk

At the 2024 European Society of Cardiology Congress, new data revealed that nearly 40% of patients with acute coronary syndrome were deemed low risk according to the Atherosclerotic Cardiovascular Disease risk score, while 12% were considered borderline risk. Lead authors Amir Ahmadi, MD, a cardiologist at Mount Sinai Foster Heart Hospital Morningside and assistant professor at the Icahn School of Medicine, and Anna Mueller, MD, an internal medicine resident, emphasized the need for new screening approaches that focus on directly detecting coronary disease, rather than relying solely on symptom-based risk scores, suggesting that technologies like CT scans could revolutionize heart disease detection and treatment.

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3. Empathetic Endings: Dr Ana Lacerda on Navigating End-of-Life Care for Pediatric Patients With Hematologic Diseases

Ana Lacerda, MD, MSc, pediatric oncologist and head of the pediatric palliative care team at the Portuguese Institute of Oncology, emphasized the importance of integrating palliative care early in the disease process for pediatric patients with hematologic diseases. During her presentation at the European Hematology Association 2024 Congress, she highlighted the challenges of end-of-life care for these children, noting how it differs from adult care and the necessity of aligning treatment with the preferences and values of patients and their families. Lacerda stressed the need for improved awareness and early palliative care integration across health care providers, families, and society.

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2. What Happens to Patients With Diabetes When Semaglutide Dosing Is Disrupted? Dr Ian Neeland Explains

Ian Neeland, MD, the director of cardiovascular prevention and co-director of the Center for Integrated and Novel Approaches in Vascular-Metabolic Disease at the University Hospitals Harrington Heart and Vascular Institute, as well as associate professor of medicine at Case Western Reserve University School of Medicine, highlighted the potential long-term consequences for patients with diabetes forced to switch medications due to the semaglutide shortage, including the risk of losing glycemic control and experiencing uncontrolled diabetes symptoms and other adverse events. Neeland stressed that while alternative medications exist, they may not offer the same cardiovascular or kidney benefits, and switching medications could lead to side effects or destabilize blood sugar control, especially if patients restart medications at their previous doses. Education and careful management are essential to mitigate these risks.

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1. Dr Phaedra Corso Discusses How to Incorporate Economic Research Into Health Policy

Phaedra Corso, PhD, associate vice president for research at Indiana University, emphasized the importance of considering cost-effectiveness in public health interventions to optimize resource allocation and impact. She noted that while there is good evidence on the effectiveness of public health interventions, policy makers often face challenges due to a lack of economic research, particularly in assessing cost-effectiveness. Additionally, the focus on intermediate outcomes, like cases prevented, rather than long-term outcomes like lives saved, complicates the integration of economic evidence into policy decisions.

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