Top 5 Most-Read Colorectal Cancer Articles of 2024

Articles on colonoscopy guidelines, the relationship between diabetes and colorectal cancer (CRC), and the decreasing rate of colonoscopies by family physicians were among the topics covered by the top 5 most-read articles about CRC on AJMC.com.

These are the top 5 articles for CRC in 2024.

5. Rate of Colonoscopies Performed by Family Physician Decreased in United States

The rate of family physicians performing colonoscopies has decreased in the US between 2016 and 2021. The number of colonoscopies performed by a family physician decreased from 11.32% in 2016 to 6.73% in 2021. Patients were more likely to receive their colonoscopy from a family physician if they were older, were men, had coinsurances or a deductible charge, lived in a rural area, or lived in the Midwest. Lower mean coinsurance, co-pay, and deductible amounts were found in patients who had their colonoscopy performed by a family physician.

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4. Cost Effectiveness Varies in TAS-102 Plus Bevacizumab Third Line Treatment

Trifluridine/tipiracil (TAS-102) plus bevacizumab was found to be a cost-effective third-line treatment in patients with CRC living in China whereas the treatment was not found to be cost-effective in the US and UK. The incremental cost-effectiveness ratios totaled $388,171/quality-adjusted life years (QALYs) in the US, $69,617/QALYs in the UK, and $20,919/QALYs in China; China’s was the only ratio that was below the willingness to pay threshold.

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Articles about colonoscopies and colonoscopy guidelines were the most read articles about colorectal cancer in 2024 | Image credit: mi_viri - stock.adobe.com

3. New Recommendations, Quality Indicators for Colonoscopy Released

The American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy released their updated guidelines for colonoscopy in August 2024, which included updated quality indicators to measure the quality of the colonoscopy. Colonoscopy acts as the primary method of screening for CRC, making the quality of the procedure paramount to ensuring prevention of CRC. These guidelines marked the second update of the guidelines since they were first published in 2006. Adenoma detection rate, rate of using recommended screening and surveillance levels, and cecal intubation rate remained important quality indicators.

Read the full article here.

2. Type 2 Diabetes Associated With Reduced Survival in Patients With CRC

Type 2 diabetes can affect the 5-year survival of patients with CRC according to a study. The 5-year overall survival rate was 82.23% in the group with comorbidities compared with 94.40% and 90.32% in the noncomorbidity group before and after a propensity score match. This extended to the groups with good blood glucose and bad blood glucose, with the overall survival being 97.14% in the former and 62.96% in the latter. The 5-year mortality risk was higher in the comorbidity group compared with the noncomorbidity group (HR, 2.275; 95% CI, 1.022-5.067).

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1. Updated Colonoscopy Guidelines Have Implications on Doctors, Patients Alike

Updated guidelines regarding the quality indicators for colonoscopy were released in August 2024 by the American College of Gastroenterology and the American Society for Gastrointestinal Endoscopy. The major updates included adding new quality indicators for measuring the quality of a colonoscopy, including bowel preparation adequacy rate and sessile serrated lesion detection rate. This article featured interviews with doctors who had varying opinions on how effective these indicators are in assessing quality and regarding the guidelines overall.

Read the full article here.