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Segment 9 - Safety Concerns with Oncolytic Virus Therapies
Although the oncolytic virus therapy being used in the OPTIM trial has been modified in a way that there should be minimal safety concerns, it should still be handled in a way to limit adverse effects and mutations, according to Kimberly Shafer-Weaver, PhD.
Although the oncolytic virus therapy being used in the OPTIM trial has been modified in a way that there should be minimal safety concerns, it should still be handled in a way to limit adverse effects and mutations, according to Kimberly Shafer-Weaver, PhD.
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“I think early on, it would really be good to set some standards to ensure that it is being handled in a way that is not only safe for those who are administrating it and the patient, but also that you have quality control over the product,” she said.
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However, she did admit to concerns about controlling the level of GM-CSF production to ensure there is not a cytokine storm in a patient.
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