- Center on Health Equity & Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Literature: Germline BRCA Mutations Increase Susceptibility to Salivary Gland Cancer
The study, published online in JAMA Otolaryngology - Head & Neck Surgery, found a significant increase in the rate of head and neck cancers in individuals carrying a BRCA mutation.
5754 individuals from 187 pedigrees were included in the cohort. Previous research has identified a link between salivary gland cancer and breast cancer, which formed the basis of the current study.
From the 5754 individual cohort, 2 parotid gland cancers, 2 salivary gland cancers not otherwise specified, and 1 adenoid cystic carcinoma were identified.
BRCA
BRCA
BRCA
P
One of these cancers likely did not segregate with the mutation, and another individual tested negative for the mutation, resulting in a rate of 3 of 5754 (0.052%). The observed rate of 3 of 5754 cases (0.052%) of head and neck cancers in -positive probands and likely carriers is significantly higher than the background incidence rate of 3 of 100,000 (0.003%) per year ( < .001).
The Clinical Cancer Genetics Program at The Ohio State University Wexner Medical Center. A total of
In this retrospective review, the authors evaluated several pedigrees of patients who were diagnosed with breast cancer in
Link to the journal article: http://bit.ly/1BAqxUz
Link to Rebecca Nagy's (senior author on the paper) participation in AJMC's panel discussion on genetic counseling: http://bit.ly/1vjffSr
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
Listen
