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AJMC® in the Press, November 9, 2018
Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.
OBR Oncology’s Thursday daily newsfeed included an article from The American Journal of Managed Care® (AJMC®). The article, “Azar Announces Mandatory Oncology Payment Model is Coming,” covered the HHS secretary’s announcement that the administration will revisit mandatory models that it had previously scrapped in cardiac care and that the time had come for “exploring new and improved episode-based models in other areas, including radiation oncology.”
AJMC®’s The Center for Biosimilars®’ article “FDA Approves Coherus’ Pegfilgrastim Biosimilar, Udenyca” was highlighted in OBR Oncology's Monday daily newsfeed. The article reported that, after previous US regulatory setbacks, the manufacturer had gained approval for its biosimilar, referencing Neulasta, to decrease the incidence of infection, as manifested by febrile neutropenia, in patients receiving myelosuppressive chemotherapy associated with a clinically significant incidence of febrile neutropenia.
The Long-term Social Value of Granulocyte Colony-Stimulating Factors
October 4th 2019Although currently underutilized, granulocyte colony-stimulating factor prophylaxis as supportive cancer care provides substantial value to society. Aligning utilization with clinical guidelines would increase this value considerably.
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Patients with hematologic malignancy who are undergoing chemotherapy or a conditioning regimen for hematopoietic stem cell transplant (HSCT) are at high risk of infection because of the severity and duration of neutropenia. Fever with neutropenia is a common presentation that suggests an infection leading to empiric antibacterial therapy. To prevent infection and thus the neutropenic fever, antibacterial prophylaxis, especially with fluoroquinolones, emerged as a common practice based on results of 2 randomized controlled trials published in 2005 that showed reduced incidence of fever and bacteremia despite lack of a mortality benefit.
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Neutropenia Etiology Influences Resulting Hematologic Consequences
March 2nd 2019Hematological consequences of severe chronic neutropenia vary based on the underlying etiology of the condition, according to a study abstract presented at the 60th American Society of Hematology Annual Meeting & Exposition.
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Home Monitoring Device for Blood Cell, Neutrophil Counts Shows Positive Initial Results
February 22nd 2019Initial results of a study have found that white blood cell counts and absolute neutrophil counts, which are well-established predictors of risk of infections or febrile neutropenia, can be accurately measured with a finger stick drop of blood and point-of-care hematology results.
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