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Hormonal Imbalance in Adult Survivors of Pediatric Cranial Tumors Reported
Investigators at St. Jude Children's Research Hospital found that decades after undergoing cranial irradiation for childhood cancer, adult survivors remain at risk for pituitary hormone deficiencies that may diminish their health and quality of life.
Investigators at St. Jude assessed the levels of pituitary hormones growth hormone, luteinizing hormone/follicle-stimulating hormone, thyroid-stimulating hormone, and adrenocorticotropic hormone) in adults who had undergone cranial radiotherapy following a childhood cancer.
The 748 participants in the study who had received cranial radiotherapy, included 394 men (mean age 34.2 years) who were observed for a mean of 27.3 years. The study examined the associations between demographic and treatment-related risk factors and pituitary deficiencies, as well as associations between untreated deficiencies and cardiovascular health, bone mineral density, and physical fitness.
The authors observed anterior pituitary deficits following cranial radiotherapy. Additonally, continued development of growth hormone deficiency and deficiencies in luteinizing hormone/follicle-stimulating hormone were observed, with possible associations between nontreatment of these conditions and poor health outcomes.
The paper has been published in The Journal of Clinical Oncology: http://bit.ly/1JmmBji
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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Uniting to Support Patients With Cancer Beyond Treatment
November 17th 2024Kasey Bond, MPH, of Perlmutter Cancer Center at NYU Langone Health, speaks to why it’s vital to keep patients at the center of all strategic partnerships between academic institutions and community-based oncology practices.
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Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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Bridging Cancer Care Gaps and Overcoming Medical Mistrust
November 13th 2024In this clip from our interview with Oscar B. Lahoud, MD, cochair of our Institute for Value-Based Medicine® evening hosted with NYU Langone Health, he addressed medical mistrust in underrepresented communities.
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How English- and Spanish-Preferring Patients With Cancer Decide on Emergency Care
November 13th 2024Care delivery innovations to help patients with cancer avoid emergency department visits are underused. The authors interviewed English- and Spanish-preferring patients at 2 diverse health systems to understand why.
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