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ESMO 2014: Nivolumab Promise in Melanoma
Results from the CheckMate-037 trial showed a significant increase in duration of response in patients with advanced melanoma administered nivolumab as second- or third-line therapy
In the first phase 3 trial to be reported with the investigational immunotherapy nivolumab, the drug showed an "impressive" duration of response when used as a second- or third-line therapy in patients with advanced melanoma, said Jeffrey Weber, MD, from the Comprehensive Melanoma Research Centers of Excellence at the Moffitt Cancer Center in Tampa, Florida. These data have been filed for approval in both Europe and the United States, where the drug has breakthrough status.
Dr. Weber was speaking at a press briefing here at the European Society for Medical Oncology (ESMO) Congress 2014, ahead of the presidential session where he presented preliminary results from the phase 3 trial, known as CheckMate-037.
The trial compared nivolumab with chemotherapy in 405 patients with unresectable advanced or metastatic melanoma who had previously been treated with (Yervoy). About 30% of these patients harbored BRAF mutations, and this group had also received treatment with a BRAF inhibitor. These patients currently have few treatment options, he commented.
Report on Medscape: http://bit.ly/1nAYMKI
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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Uniting to Support Patients With Cancer Beyond Treatment
November 17th 2024Kasey Bond, MPH, of Perlmutter Cancer Center at NYU Langone Health, speaks to why it’s vital to keep patients at the center of all strategic partnerships between academic institutions and community-based oncology practices.
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Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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Bridging Cancer Care Gaps and Overcoming Medical Mistrust
November 13th 2024In this clip from our interview with Oscar B. Lahoud, MD, cochair of our Institute for Value-Based Medicine® evening hosted with NYU Langone Health, he addressed medical mistrust in underrepresented communities.
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How English- and Spanish-Preferring Patients With Cancer Decide on Emergency Care
November 13th 2024Care delivery innovations to help patients with cancer avoid emergency department visits are underused. The authors interviewed English- and Spanish-preferring patients at 2 diverse health systems to understand why.
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