During this segment, the panelists conclude that although treatment guidelines are now being developed to help practitioners consider therapy options for patients with systemic lupus erythematosus (SLE), there are still factors that need to be addressed.
Michelle Petri, MD, MPH, explains that there are now 3 clinical practice guidelines for the treatment of lupus, whereas in the past there were none. The American College of Rheumatology, Systemic Lupus International Collaborating Clinics, and European League Against Rheumatism guidelines exhibit consistencies about how to treat patients with lupus.
However, Dr Petri explains that the guidelines need to address how to treat patients who fail suggested induction therapies. Dr Petri believes that flexibility is key due to the need to individualize therapy for patients in instances of poor outcomes.
Dr Petri feels that our country is still in the “dark ages” in regard to addressing the needs of patients with SLE. She explains that because SLE is a rare disease, there is still no FDA-approved gold standard for treating the disease.
Agreeing with Dr Petri, Maria Lopes, MD, MS, believes that there is a need for personalized therapy, which requires an in-depth, collaborative discussion about how to treat a patient as an individual before beginning therapy.
Managed Care Reflections: A Q&A With A. Mark Fendrick, MD, and Michael E. Chernew, PhD
December 2nd 2025To mark the 30th anniversary of The American Journal of Managed Care (AJMC), each issue in 2025 includes a special feature: reflections from a thought leader on what has changed—and what has not—over the past 3 decades and what’s next for managed care. The December issue features a conversation with AJMC Co–Editors in Chief A. Mark Fendrick, MD, director of the Center for Value-Based Insurance Design and a professor at the University of Michigan in Ann Arbor; and Michael E. Chernew, PhD, the Leonard D. Schaeffer Professor of Health Care Policy and the director of the Healthcare Markets and Regulation Lab at Harvard Medical School in Boston, Massachusetts.
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