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Episode 3 - The CHAARTED Study-Treatment of CRPC with Docetaxel
In this segment, Christopher Sweeney, MBBS, provides an overview of the ChemoHormonal Therapy versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer (CHAARTED) and discusses how the results of the trial have impacted the treatment of patients with prostate cancer.
Dr Sweeney, an active player in the 10-year trial, notes that the results of the trial showed that in patients who experienced disease progression, overall survival was improved in patients treated with chemotherapy (docetaxel) plus androgen deprivation therapy (ADT) compared with patients who received only ADT.
The results of the CHAARTED trial have led to additional clinical trials that further explore the use of newer agents such as abiraterone or enzalutamide in combination with chemotherapy, adds Dr Sweeney. Specifically, he remarks that 2 specific combination therapy strategies are currently being assessed in clinical studies: horizontal inhibition and vertical inhibition.
Watch our related Peer Exchange, Oncology Stakeholder Summit 2014: Evidence-Based Decisions to Improve Quality and Regulate Costs
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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FDA Approves Danziten for Chronic Myeloid Leukemia Without Mealtime Restrictions
November 14th 2024The FDA has granted approval to Azurity Pharmaceuticals' nilotinib tablets (Danziten), a novel version of the tyrosine kinase inhibitor for chronic myeloid leukemia that can be taken without mealtime restrictions.
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Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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How English- and Spanish-Preferring Patients With Cancer Decide on Emergency Care
November 13th 2024Care delivery innovations to help patients with cancer avoid emergency department visits are underused. The authors interviewed English- and Spanish-preferring patients at 2 diverse health systems to understand why.
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