In part 2 of our interview, Yehuda Handelsman, MD, discusses how cardiorenalmetabolic (CRM) disease management is advancing with the 2022 Diabetes, Cardiorenal, and Metabolic (DCRM) multispecialty practice recommendations and the updated DCRM 2.0 guidelines.
In part 2 of our interview with Yehuda Handelsman, MD, medical director and principal investigator at the Metabolic Institute of America, he explained that cardiorenalmetabolic (CRM) disease management is progressing toward a more integrated and practical approach after the 2022 Diabetes, Cardiorenal, and Metabolic (DCRM) multispecialty practice recommendations and the recently updated DCRM 2.0 guidelines helped to simplify care, promote global collaboration, and highlight the importance of early, comprehensive management for patients with multiple comorbidities.
He expands upon this topic in part 1 of the interview and his report, “Diabetes, Cardiorenal, and Metabolic Multispecialty Practice Recommendations and Early Intensive Management of Cardio-Renal-Metabolic Disease,” featured in the December 2024 American Journal of Managed Care® supplement, “Optimal Management of Patients With Cardio-Kidney-Metabolic Syndrome.”
This transcript has been lightly edited for clarity.
Transcript
Looking ahead, how do you see CRM disease management evolving? In your opinion, what role will the DCRM recommendations play in shaping these changes?
I think the recognition will come forward. Recently, the American Heart Association came up with a presidential statement or consensus on cardiovascular-kidney-metabolic health, so CKM, still a very good construct. Professional-like, more CRM, I think CKM may be a good language for patient care. Cardio-kidney vs cardio-renal, it doesn't matter, the knowledge of the conditions has become much more prevailed, so I think more people will come up with recommendations as we did; our recommendation is practical.
The original DCRM has reached more than a million people internationally. We have networks of primary care physicians and specialists using the DCRM because it makes it easy for them. In some cases, it's part of their networks. We know that networks in India that is connected to networks in New Mexico and Houston have been using it. I, myself, have given lectures in anywhere from places in Europe to Egypt, China, the Philippines, and India. People like this concept, and I know that it's been shown by many experts, a lot of them not involved with our group, but they found it very helpful.
Right now, I'm getting requests from all over the world to send it [DCRM recommendations], and it's available for free. What they [experts] say is that maybe our need is to create guidelines and practice accommodations in a simple way so people don't need to read a textbook and can look directly at how we can simply help patients. We will try to incorporate it into EMRs [electronic medical records] to make it much easier, both through diagnosis and management, and for people to recognize that the more conditions that a DCRM patient has, the more complications or comorbidities, the higher the risk they have to die, the higher the risk they have to get to an end-stage disease of one type or another. So, the urgency to manage them earlier and with different drugs in different classes and combinations is very important. So, hopefully, that urgency will come.
I have a comment for leadership from the different medical societies, that they will also find ways to come together. So like we, as individuals, most of us leaders in different medical societies, together we came. Hopefully, the medical societies can perhaps do something similar and give equal footing to kidney, heart, liver, diabetes, blood pressure, and obesity and not necessarily what's important to one medical society or another. So, let's work together for the patient's benefit.
Disparities in Biomarker Testing Impact Nonsquamous NSCLC Outcomes: Surbhi Singhal, MD
September 6th 2025Surbhi Singhal, MD, of the University of California Davis, discussed disparities in biomarker testing among patients diagnosed with stage IV nonsquamous non–small cell lung cancer (NSCLC).
Read More
Infertility Coverage Boosts ART Use and Pregnancy Success: Richard A. Brook, MS, MBA
August 26th 2025In this episode, Richard A. Brook, MS, MBA, discusses his study showing that infertility treatment coverage increases assisted reproductive technology (ART) use and improves pregnancy outcomes.
Listen
Economic Burden Is Greater Among Patients With Ovarian Cancer Receiving BRCA Testing
September 4th 2025Patients with ovarian cancer who undergo BRCA testing face higher health care resource utilization (HCRU) and costs but are more likely to receive genomically targeted therapies and progress to later lines of treatment (LOT).
Read More
Hope on the Horizon for Underserved Patients With Multiple Myeloma: Joseph Mikhael, MD
August 12th 2025Explore the disparities in multiple myeloma treatment and how new initiatives aim to improve clinical trial participation among underrepresented patients during a conversation with Joseph Mikhael, MD, MEd, FRCPC, FACP, FASCO, chief medical officer of the International Myeloma Foundation.
Listen
ACC017 Showed Safety, Tolerability When Used as Antiretroviral Therapy
September 4th 2025New abstracts from the 26th International Workshop on Clinical Pharmacology of HIV, Hepatitis, and Other Antiviral Drugs 2025 found that ACC017 showed promise in its use as an antiretroviral therapy.
Read More
Prevention, Early Intervention Highlighted in Updated High Blood Pressure Guidelines
September 4th 2025A new joint guideline from the American Heart Association and the American College of Cardiology emphasizes early treatment, close perinatal blood pressure monitoring, and incorporating the PREVENT risk calculator to personalize care.
Read More