- Center on Health Equity & Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Dr Michel Michaelides Speaks About Implications of Gene Therapy Study Results in Ophthalmology
The results of a study showing improved functional vision and retinal sensitivity have implications for gene therapy in ophthalmological conditions, explained Michel Michaelides, MD, FACP, a consultant ophthalmologist and a professor of ophthalmology at the University College London Institute of Ophthalmology's Genetics Department.
Michel Michaelides, MD, FACP, explained what research findings presented at the American Academy of Ophthalmology (AAO) 2022 Conference could mean for the potential of gene therapy to improve functional vision and retinal sensitivity in patients with retinitis pigmentosa.
Transcript
What were some of the results from your study that was presented at AAO 2022 and what do they say about the potential for the investigational gene therapy botaretigene sparoparvovec (bota-vec)?
We presented our phase 1/2 data of the entire trial and also including the randomized controlled expansion phase. And what was exciting was that, in addition to the safety that we've previously alluded to, we were able to show that, comparing treated patients to a concurrent control group, there were significant improvements in both retinal sensitivity and functional vision. And I was particularly excited about the functional vision because that's what patients can do with the improvement in their retinal sensitivity and, arguably, that's the most important thing.
BCI Shows Promise of Personalized Endocrine Therapy in Breast Cancer
January 15th 2025The Breast Cancer Index (BCI) may help identify patients with low-risk breast cancer who could potentially benefit from reduced endocrine therapy, leading to improved quality of life and potentially lower health care costs.
Read More
Managed Care Cast Presents: BTK Inhibitors in Treatment-Naive Patients With CLL and MCL
December 26th 2024A trio of experts discuss the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) with Bruton tyrosine kinase (BTK) inhibitors, including cost considerations.
Listen
Designing Care for the Underserved Creates Higher-Value Health Solutions
January 12th 2025In the second half of our interview with Brita Roy, MD, MPH, MHS, NYU Grossman School of Medicine, she discusses effective engagement of minoritized populations in discussion of medical mistrust.
Read More
AI's Role in Oncology: Supporting, Not Replacing, Health Care Providers
January 9th 2025In this second half of our interview with Vanderbilt University Medical Center’s Travis Osterman, DO, MS, FAMIA, FASCO, he discusses opportunities for advancing the smart use of artificial intelligence (AI) in cancer care.
Read More
