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Breast Cancer Susceptibility Increases With Age and Weight: JAMA Study
A Women's Health Initiative clinical trial has found that overweight or obese postmenopausal women are at an increased risk of aggressive breast cancer.
Published in JAMA Oncology, a randomized clinical trial by the Women's Health Initiative followed 67,142 postmenopausal women with annual or biennial mammography across 40 sites around the country. The women, between 50 and 79 years of age, were followed for a median of 13 years.
The study found that compared with women of normal weight, those who were classified as overweight or obese had a greater risk of developing invasive breast cancer than those who were overweight or obese. Some of the findings of the study include:
- BMI of ≥35, high risk of estrogen receptor—positive breast cancer
- Obesity grade 2 and 3 associated with advanced breast cancer, including large tumor size, positive lymph nodes, and death
- Women who gained >5% body weight during follow-up were at an increased risk of breast cancer
The authors conclude that this study should motivate obesity prevention programs.
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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Higher Life’s Essential 8 Scores Associated With Reduced COPD Risk
November 21st 2024Higher Life’s Essential 8 (LE8) scores, especially those reflecting lower nicotine exposure and better sleep health, are inversely associated with chronic obstructive pulmonary disease (COPD) risk, emphasizing the importance of cardiovascular health (CVH) in disease prevention.
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