Combining nab-paclitaxel with nivolumab is expected to have a synergistic effect in the various tumor types to be targeted, while providing Celgene access to the immunooncology race.
Bristol-Myers Squibb ($BMY) and Celgene ($CELG) are joining forces on a cancer combination treatment, testing the former's highly anticipated immunotherapy in tandem with an on-the-market chemo drug against a host of tumor targets.
The plan is to launch a Phase I study pairing Bristol-Myers' nivolumab, a cancer treatment designed to bring about the death of tumor cells by blocking a pathway called PD-1; and Celgene's Abraxane, an injectable form of the chemotherapy paclitaxel already approved to treat pancreatic, prostate, breast and lung cancers.
The hope is that combining nivolumab's effect on the immune system with Abraxane's ability to halt cancer cell division will result in a therapy greater than the sum of its parts, the companies said, and they plan to kick off their trial in the fourth quarter of this year. Among their targets are HER-2 negative metastatic breast cancer, pancreatic cancer and non-small cell lung cancer.
Associated press release: http://bit.ly/VFBXbc
Read the news here: http://bit.ly/1uX1yfb
Source: Fierce Biotech
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
Listen
Texas Oncology to Roll Out Canopy for ePROs After Head-to-Head Pilot
March 18th 2025Debra Patt, MD, PhD, MBA, executive vice president of Public Policy and Strategy for Texas Oncology, said the practice received positive feedback from nurses and patients during a pilot that concluded in February.
Read More
Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
Listen