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AstraZeneca Investing in Blood Test to Personalize NSCLC Treatment
AstraZeneca has signed up Roche and Qiagen to develop two separate diagnostic tests, both using simple blood samples, to identify patients who will benefit from its lung cancer drugs.
Currently testing patients to see if their tumors contain genetic mutations that make them suitable for drug treatment involves collecting a sample of tissue by needle biopsy or during surgery.
The new tests are based on smart technology that can detect small fragments of circulating tumor DNA in the plasma taken from patients' blood.
The collaboration with Qiagen involves developing such a test to accompany AstraZeneca's established lung cancer pill Iressa, while the agreement with Roche is for a companion diagnostic to go with AstraZeneca's experimental successor to Iressa called AZD9291.
AZD9291 targets a genetic mutation that helps tumors evade existing treatments and AstraZeneca believes it could sell as much as $3 billion a year. The mutation, known as T790M, develops in about half of lung cancers that become resistant to current epidermal growth factor receptor inhibitors like Iressa.
Read the original report here: http://reut.rs/1oAmSU3
Source: Reuters
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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Uniting to Support Patients With Cancer Beyond Treatment
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April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
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Bridging Cancer Care Gaps and Overcoming Medical Mistrust
November 13th 2024In this clip from our interview with Oscar B. Lahoud, MD, cochair of our Institute for Value-Based Medicine® evening hosted with NYU Langone Health, he addressed medical mistrust in underrepresented communities.
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How English- and Spanish-Preferring Patients With Cancer Decide on Emergency Care
November 13th 2024Care delivery innovations to help patients with cancer avoid emergency department visits are underused. The authors interviewed English- and Spanish-preferring patients at 2 diverse health systems to understand why.
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