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Anti-MET Antibody Fails to Impress in Phase 3 NSCLC Trial
Onartuzumab (MetMab)did not improve PFS when combined with erlotinib (Tarceva) in the METLung trial.
Adding the novel anti-MET monoclonal antibody onartuzumab (MetMab) to EGFR mutation-targeted therapy did not impact outcomes in a pivotal trial, although other findings suggested it may have been the population rather than the target at fault.
Progression-free survival came out nearly identical for the drug added to erlotinib (Tarceva) as with erlotinib alone (median 2.7 versus 2.6 months, P=0.92), David R. Spigel, MD, of the Sarah Cannon Research Institute in Nashville, Tenn., and colleagues found in the METLung trial.
Overall survival actually trended in favor of erlotinib alone (9.1 months versus 6.8 on the combination, P=0.07), the group reported here at the American Society of Clinical Oncology meeting.
Read the report here: http://bit.ly/1kNH8uO
Source: Medpage Today
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
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