- Center on Health Equity & Access
- Clinical
- Health Care Cost
- Health Care Delivery
- Insurance
- Policy
- Technology
- Value-Based Care
Amgen's Kyprolis Fails in Phase 3 MM Trial
Kyprolis failed to improve survival in the phase 3 FOCUS trial in patients who had relapse following at least 3 prior regimens.
Amgen Inc's Kyprolis drug failed to extend survival compared to standard care in a trial involving patients with advanced multiple myeloma, a type of blood cancer that develops in the bone marrow.
Shares of Amgen were down 2.1 percent at $124.65 in after-hours trading on Wednesday.
"The negative results commercialization of this drug in earlier lines of myeloma, as well as other indications raise questions about the future development and ," Sanford Bernstein analyst Geoffrey Porges said in a research note.
He also said the findings "place Kyprolis at a significant regulatory and competitive disadvantage" to Pomalyst, a multiple myeloma drug sold by Celgene Corp.
Amgen said the 315-patient, phase III trial also showed an increase in bad kidney events for patients given Kyprolis when compared to the control group and to the risks described on the drug's current label.
Original report: http://reut.rs/1sG1LTi
Source: Reuters
Exploring Racial, Ethnic Disparities in Cancer Care Prior Authorization Decisions
October 24th 2024On this episode of Managed Care Cast, we're talking with the author of a study published in the October 2024 issue of The American Journal of Managed Care® that explored prior authorization decisions in cancer care by race and ethnicity for commercially insured patients.
Listen
Uniting to Support Patients With Cancer Beyond Treatment
November 17th 2024Kasey Bond, MPH, of Perlmutter Cancer Center at NYU Langone Health, speaks to why it’s vital to keep patients at the center of all strategic partnerships between academic institutions and community-based oncology practices.
Read More
Examining Low-Value Cancer Care Trends Amidst the COVID-19 Pandemic
April 25th 2024On this episode of Managed Care Cast, we're talking with the authors of a study published in the April 2024 issue of The American Journal of Managed Care® about their findings on the rates of low-value cancer care services throughout the COVID-19 pandemic.
Listen
Bridging Cancer Care Gaps and Overcoming Medical Mistrust
November 13th 2024In this clip from our interview with Oscar B. Lahoud, MD, cochair of our Institute for Value-Based Medicine® evening hosted with NYU Langone Health, he addressed medical mistrust in underrepresented communities.
Read More
How English- and Spanish-Preferring Patients With Cancer Decide on Emergency Care
November 13th 2024Care delivery innovations to help patients with cancer avoid emergency department visits are underused. The authors interviewed English- and Spanish-preferring patients at 2 diverse health systems to understand why.
Read More
