This supplement to The American Journal of Managed Care reviews the pathophysiology, symptoms and clinical course, and diagnostic challenges of hereditary angioedema (HAE). The current therapeutic landscape for HAE is discussed with a focus on treatment for acute angioedema attacks, short- and long-term HAE prophylaxis, and home-based therapy. The supplement also describes the economic burdens of HAE, both direct and indirect, and how changes in treatment practices, such as the wider adoption of homebased therapy, may improve patient outcomes and reduce costs.Faculty
William J. Cardarelli, PharmD
Director of Pharmacy Revenue and Supply
Atrius Health
Harvard Vanguard Medical Associates
Watertown, Massachusetts
William R. Lumry, MD
Clinical Professor of Internal Medicine/Allergy
University of Texas Southwestern Medical School
Medical Director, AARA Research Center
Private Practice
Dallas, Texas
Contributing Editorial Support
Roderick A. Smith, MS
Medical-Science Communications Expert
Brighton, Massachusetts
This activity is supported by an educational grant from ViroPharma Incorporated.
Faculty Disclosures
These faculty have disclosed the following relevant commercial financial relationships or affiliations in the past 12 months.
William J. Cardarelli, PharmD, has no relevant financial relationships with commercial interests to disclose.
William R. Lumry, MD
Consultant: Biocryst, CSL Behring, Shire Human Genetic Therapies, ViroPharma Incorporated
Grants: CSL Behring, Dyax, Shire Human Genetic Therapies, ViroPharma Incorporated
Speakers’ Bureau: CSL Behring, Dyax, Shire Human Genetic Therapies, ViroPharma Incorporated
Roderick A. Smith, MS, has no relevant financial relationships with commercial interests to disclose.
The American Journal of Managed Care
Publishing Staff—Jeff D. Prescott, PharmD, RPh; Kara Guarini, MS; and Ida Delmendo have no relevant financial relationships with commercial interests to disclose.
PER and Pharmacy Times Office of Continuing Professional Education
Planning Staff—Judy V. Lum, MPA; and Elena Beyzarov, PharmD, and Ann C. Lichti, CCMEP, have no relevant financial relationships with commercial interests to disclose.
Signed disclosures are on file at the office of The American Journal of Managed Care, Plainsboro, New Jersey.
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