EP. 1: Overview of Generalized Pustular Psoriasis
Mark G. Lebwohl, MD, gives an overview of generalized pustular psoriasis (GPP) and explains how it differs from the more common plaque psoriasis.
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EP. 2: Causes and Triggers of Generalized Pustular Psoriasis
Mark G. Lebwohl, MD, explains what causes generalized pustular psoriasis (GPP) and the potential triggers for GPP episodes.
EP. 3: IL-36 and Other Mutations in Generalized Pustular Psoriasis
Mark G. Lebwohl, MD, discusses how IL-36 mutations can play a part in disease presentation and how IL-17 and IL-23 pathways are more often implicated in plaque psoriasis.
EP. 4: Disease Severity and Treatment Setting of GPP
Aaron Farberg, MD, and Maria Lopes, MD, MS, discuss what makes generalized pustular psoriasis a potentially life-threatening condition and where patients with the disease typically present and receive treatment.
EP. 5: Economic Burden of Generalized Pustular Psoriasis
Mark G. Lebwohl, MD, and Maria Lopes, MD, MS, review the incidence and prevalence of generalized pustular psoriasis as well as direct and indirect costs associated with the disease.
EP. 6: Impact of Generalized Pustular Psoriasis on Patients
Aaron Farberg, MD, and Mark G. Lebwohl, MD, discuss the relapsing nature of generalized pustular psoriasis and how the difficulty in diagnosing the disease affects outcomes for patients.
EP. 7: Quality of Life of Patients with GPP
Aaron Farberg, MD, and Mark G. Lebwohl, MD, review the biggest unmet needs of patients with generalized pustular psoriasis (GPP) and the impact GPP has on their quality of life.
EP. 8: Reducing the Impact GPP has on Quality of Life
Maria Lopes, MD, MS, and Mark G. Lebwohl, MD, discuss how the impact that generalized pustular psoriasis (GPP) has on quality of life can be reduced and how the effects are measured in practice.
EP. 9: Comorbidities of Generalized Pustular Psoriasis
Aaron Farberg, MD, and Mark G. Lebwohl, MD, discuss the common comorbidities seen in patients with generalized pustular psoriasis (GPP) and some potential future developments in the management of GPP.
EP. 10: Approved Medications for GPP
Aaron Farberg, MD, reviews medications that are approved to treat generalized pustular psoriasis and the potential role of combination therapy.
EP. 11: Role of Topical Treatments in GPP Treatment
Mark G. Lebwohl, MD, explores the role of topical treatments such as corticosteroids and tacrolimus in treating generalized pustular psoriasis (GPP) and important safety considerations.
EP. 12: Considerations for Spesolimab Use for GPP
Maria Lopes, MD, MS, explains how the setting of care for spesolimab may impact coverage policies and access to the medication.
EP. 13: Minimizing Treatment Delays in GPP
Maria Lopes, MD, MS, reviews how clinicians and payers can work together to minimize any potential treatment delays, ensuring patients receive needed care in the timeliest manner.
EP. 14: Reducing the Hospital Stay for Patients With GPP
Aaron Farberg, MD, and Mark G. Lebwohl, MD, explore the typical hospital length of stay for patients with an acute generalized pustular psoriasis (GPP) flare, and define treatment success with GPP therapies.
EP. 15: Final Thoughts on Generalized Pustular Psoriasis
A panel of experts provide their final thoughts on generalized pustular psoriasis, the treatment for this disease, and the impact it has on patients.